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Step-emulsification in a microfluidic device

  • Z. Li
  • , A. M. Leshansky
  • , L. M. Pismen
  • , P. Tabeling
  • Centre National de la Recherche Scientifique (CNRS)
  • CNRS
  • Technion-Israel Institute of Technology

科研成果: 期刊稿件文章同行评审

摘要

We present a comprehensive study of the step-emulsification process for high-throughput production of colloidal monodisperse droplets. The 'microfluidic step emulsifier' combines a shallow microchannel operating with two co-flowing immiscible fluids and an abrupt (step-like) opening to a deep and wide reservoir. Based on Hele-Shaw hydrodynamics, we determine the quasi-static shape of the fluid interface prior to transition to oscillatory step-emulsification at low capillary numbers. The theoretically derived transition threshold yields an excellent agreement with experimental data. A closed-form expression for the size of the droplets generated in the step-emulsification regime and derived using geometric arguments also shows a very good agreement with the experiment.
源语言英语
页(从-至)1023-1031
页数9
期刊Lab on a Chip
15
4
DOI
出版状态已出版 - 2015
已对外发布

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