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Pse-Analysis: A python package for DNA/RNA and protein/ peptide sequence analysis based on pseudo components and kernel methods

  • Bin Liu*
  • , Hao Wu
  • , Deyuan Zhang
  • , Xiaolong Wang
  • , Kuo Chen Chou
  • *此作品的通讯作者
  • Harbin Institute of Technology
  • Harbin Institute of Technology Shenzhen
  • Gordon Life Science Institute
  • Shenyang Aerospace University
  • University of Electronic Science and Technology of China

科研成果: 期刊稿件文章同行评审

摘要

To expedite the pace in conducting genome/proteome analysis, we have developed a Python package called Pse-Analysis. The powerful package can automatically complete the following five procedures: (1) sample feature extraction, (2) optimal parameter selection, (3) model training, (4) cross validation, and (5) evaluating prediction quality. All the work a user needs to do is to input a benchmark dataset along with the query biological sequences concerned. Based on the benchmark dataset, Pse-Analysis will automatically construct an ideal predictor, followed by yielding the predicted results for the submitted query samples. All the aforementioned tedious jobs can be automatically done by the computer. Moreover, the multiprocessing technique was adopted to enhance computational speed by about 6 folds. The Pse-Analysis Python package is freely accessible to the public at http://bioinformatics.hitsz.edu.cn/Pse-Analysis/, and can be directly run on Windows, Linux, and Unix.

源语言英语
页(从-至)13338-13343
页数6
期刊Oncotarget
8
8
DOI
出版状态已出版 - 2017
已对外发布

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