Preparation of Spiro[indene-1,1′-isoindolin]-3′-ones via Sulfuric Acid-Promoted Cascade Cyclization

Lang Sun; Peng Liu; Jing Wang; Ping Lu; Yanguang Wang

doi:10.1021/acs.joc.7b00958

Preparation of Spiro[indene-1,1′-isoindolin]-3′-ones via Sulfuric Acid-Promoted Cascade Cyclization

Lang Sun
, Peng Liu
, Jing Wang
, Ping Lu^*
, Yanguang Wang

^*此作品的通讯作者

Zhejiang University

科研成果: 期刊稿件 › 文章 › 同行评审

18 引用（Scopus）

摘要

The sulfuric acid-promoted cascade cyclization of 2-(3-hydroxyprop-1-ynyl)benzonitriles led to an efficient synthesis of spiro[indene-1,1′-isoindolin]-3′-ones. This class of spiro compounds could also be prepared by the sulfuric acid-catalyzed cyclization of 2-(phenylacryloyl)benzonitriles, which were readily derived from 2-(3-hydroxyprop-1-ynyl)benzamides using trifluoroacetic acid as a catalyst.

源语言	英语
页（从-至）	8407-8418
页数	12
期刊	Journal of Organic Chemistry
卷	82
期	16
DOI	https://doi.org/10.1021/acs.joc.7b00958
出版状态	已出版 - 18 8月 2017
已对外发布	是

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abstract = "The sulfuric acid-promoted cascade cyclization of 2-(3-hydroxyprop-1-ynyl)benzonitriles led to an efficient synthesis of spiro[indene-1,1′-isoindolin]-3′-ones. This class of spiro compounds could also be prepared by the sulfuric acid-catalyzed cyclization of 2-(phenylacryloyl)benzonitriles, which were readily derived from 2-(3-hydroxyprop-1-ynyl)benzamides using trifluoroacetic acid as a catalyst.",

author = "Lang Sun and Peng Liu and Jing Wang and Ping Lu and Yanguang Wang",

note = "Publisher Copyright: {\textcopyright} 2017 American Chemical Society.",

year = "2017",

month = aug,

day = "18",

doi = "10.1021/acs.joc.7b00958",

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T1 - Preparation of Spiro[indene-1,1′-isoindolin]-3′-ones via Sulfuric Acid-Promoted Cascade Cyclization

AU - Sun, Lang

AU - Liu, Peng

AU - Wang, Jing

AU - Lu, Ping

AU - Wang, Yanguang

PY - 2017/8/18

Y1 - 2017/8/18

N2 - The sulfuric acid-promoted cascade cyclization of 2-(3-hydroxyprop-1-ynyl)benzonitriles led to an efficient synthesis of spiro[indene-1,1′-isoindolin]-3′-ones. This class of spiro compounds could also be prepared by the sulfuric acid-catalyzed cyclization of 2-(phenylacryloyl)benzonitriles, which were readily derived from 2-(3-hydroxyprop-1-ynyl)benzamides using trifluoroacetic acid as a catalyst.

AB - The sulfuric acid-promoted cascade cyclization of 2-(3-hydroxyprop-1-ynyl)benzonitriles led to an efficient synthesis of spiro[indene-1,1′-isoindolin]-3′-ones. This class of spiro compounds could also be prepared by the sulfuric acid-catalyzed cyclization of 2-(phenylacryloyl)benzonitriles, which were readily derived from 2-(3-hydroxyprop-1-ynyl)benzamides using trifluoroacetic acid as a catalyst.

UR - https://www.scopus.com/pages/publications/85027542785

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DO - 10.1021/acs.joc.7b00958

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AN - SCOPUS:85027542785

SN - 0022-3263

VL - 82

SP - 8407

EP - 8418

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 16

ER -

Preparation of Spiro[indene-1,1′-isoindolin]-3′-ones via Sulfuric Acid-Promoted Cascade Cyclization

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