@article{94da35d09cc8446abcf4d61f482ee70c,
title = "Organocatalytic Asymmetric Michael/Cyclization Cascade Reaction of 3-Isothiocyanato Oxindoles with Maleimides for the Efficient Construction of Pyrrolidonyl Spirooxindoles",
abstract = "The development of a Michael/cyclization cascade reaction between 3-isothiocyanato-oxindoles and maleimide catalyzed by chrial squaramides is reported. This protocol provides a series of pyrrolidonyl spirooxindoles bearing three contiguous stereocenters in excellent yields (up to 99 %) with high diastereo- and enantioselectivities (up to >99:1 dr, 91 % ee).",
keywords = "Asymmetric catalysis, Cascade reactions, Cyclization, Michael addition, Nitrogen heterocycles, Spiro compounds",
author = "Lei Liu and Zhao, {Bo Liang} and Du, {Da Ming}",
note = "Publisher Copyright: {\textcopyright} 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim",
year = "2016",
month = sep,
doi = "10.1002/ejoc.201600658",
language = "English",
volume = "2016",
pages = "4711--4718",
journal = "European Journal of Organic Chemistry",
issn = "1434-193X",
publisher = "Wiley-VCH Verlag",
number = "27",
}