TY - GEN
T1 - Optimization of Electrode Combinations for High-Performance Bilateral TIBS Stimulation
AU - Kang, Anshun
AU - Zhao, Yan
AU - Ouyang, Jian
AU - Luo, Qiwen
AU - Zhao, Jiayuan
AU - Yan, Zilong
AU - Pei, Guangying
AU - Yan, Tianyi
AU - Chen, Wenhao
AU - Wang, Li
N1 - Publisher Copyright:
© 2025 IEEE.
PY - 2025
Y1 - 2025
N2 - Temporal Interference brain stimulation is a noninvasive neuromodulation technique enabling direct electrical stimulation of deep brain regions. This study aimed to identify the optimal electrode pair combination for targeting the thalamus. Using MRI data from 26 healthy adults, individualized head models were developed and envelope fields computed to simulate electrical stimulation under various electrode configurations. Forward simulations and assessments of 998 electrode combinations within these head models revealed the F7-P7/F8-P8 combination demonstrated superior overall performance. These findings provide a foundation for establishing a targeted optimization framework for thalamic stimulation, including the selection and evaluation of reference metrics.
AB - Temporal Interference brain stimulation is a noninvasive neuromodulation technique enabling direct electrical stimulation of deep brain regions. This study aimed to identify the optimal electrode pair combination for targeting the thalamus. Using MRI data from 26 healthy adults, individualized head models were developed and envelope fields computed to simulate electrical stimulation under various electrode configurations. Forward simulations and assessments of 998 electrode combinations within these head models revealed the F7-P7/F8-P8 combination demonstrated superior overall performance. These findings provide a foundation for establishing a targeted optimization framework for thalamic stimulation, including the selection and evaluation of reference metrics.
KW - Electrode Combination Simulation
KW - Temporal Interference brain stimulation
KW - individualized model
KW - thalamic stimulation
UR - https://www.scopus.com/pages/publications/105029704556
U2 - 10.1109/CME67420.2025.11239409
DO - 10.1109/CME67420.2025.11239409
M3 - Conference contribution
AN - SCOPUS:105029704556
T3 - 2025 19th International Conference on Complex Medical Engineering, CME 2025
SP - 338
EP - 342
BT - 2025 19th International Conference on Complex Medical Engineering, CME 2025
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 19th International Conference on Complex Medical Engineering, CME 2025
Y2 - 1 August 2025 through 3 August 2025
ER -