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NOA 81 fabricated microfluidic chip for SH-SY5Y cell culture

  • Beijing Institute of Technology

科研成果: 书/报告/会议事项章节会议稿件同行评审

摘要

Microfluidic chip has been an important tool for the study of life science, especially in cell biology researches. The chip provides precise manipulation of cells and helps establish similar environment in body network. A promising material, Noland Optical Adhesive 81 (NOA 81), was adopted here to fast fabricate the chip. The material was first cured and used for cell culture directly to test the biocompatibility and then fabricated into chips. We tested the flow influence on different designs of the chip structures. Finally, SH-SY5Y cells were induced and cultured in the microfluidic chip. The results show NOA 81 has good viabilities and adherence for cell culture. Column in chamber can reduce and disperse the fluid stress efficiently. With the efficient chip design, SH-SY5Y cells can survive in chip for more than one week.

源语言英语
主期刊名2015 IEEE International Conference on Mechatronics and Automation, ICMA 2015
出版商Institute of Electrical and Electronics Engineers Inc.
994-998
页数5
ISBN(电子版)9781479970964
DOI
出版状态已出版 - 2 9月 2015
活动12th IEEE International Conference on Mechatronics and Automation, ICMA 2015 - Beijing, 中国
期限: 2 8月 20155 8月 2015

出版系列

姓名2015 IEEE International Conference on Mechatronics and Automation, ICMA 2015

会议

会议12th IEEE International Conference on Mechatronics and Automation, ICMA 2015
国家/地区中国
Beijing
时期2/08/155/08/15

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