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Mining biologically significant co-regulation patterns from microarray data

  • Yuhai Zhao*
  • , Ying Yin
  • , Guoren Wang
  • *此作品的通讯作者
  • Northeastern University China

科研成果: 书/报告/会议事项章节会议稿件同行评审

摘要

In this paper, we propose a novel model, namely g-Cluster, to mine biologically significant co-regulated gene clusters. The proposed model can (1) discover extra co-expressed genes that cannot be found by current pattern/tendency-based methods, and (2) discover inverted relationship overlooked by pattern/tendency-based methods. We also design two tree-based algorithms to mine all qualified g-Clusters. The experimental results show: (1) our approaches are effective and efficient, and (2) our approaches can find an amount of co-regulated gene clusters missed by previous models, which are potentially of high biological significance.

源语言英语
主期刊名Rough Sets and Knowledge Technology - First International Conference, RSKT 2006, Proceedings
出版商Springer Verlag
408-414
页数7
ISBN(印刷版)3540362975, 9783540362975
DOI
出版状态已出版 - 2006
已对外发布
活动First International Conference on Rough Sets and Knowledge Technology, RSKT 2006 - Chongqing, 中国
期限: 24 7月 200626 7月 2006

出版系列

姓名Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
4062 LNAI
ISSN(印刷版)0302-9743
ISSN(电子版)1611-3349

会议

会议First International Conference on Rough Sets and Knowledge Technology, RSKT 2006
国家/地区中国
Chongqing
时期24/07/0626/07/06

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