Isolation and characterization of three fungi with the potential of transforming glycyrrhizin

Chao Wang; Xiao Xiao Guo; Xiao Yan Wang; Feng Qi; Shi Jiang Feng; Chun Li; Xiao Hong Zhou

doi:10.1007/s11274-012-1233-9

Isolation and characterization of three fungi with the potential of transforming glycyrrhizin

Chao Wang
, Xiao Xiao Guo
, Xiao Yan Wang
, Feng Qi
, Shi Jiang Feng
, Chun Li^*
, Xiao Hong Zhou

^*此作品的通讯作者

化学与化工学院

Beijing Institute of Technology
Shihezi University

科研成果: 期刊稿件 › 文章 › 同行评审

20 引用（Scopus）

摘要

Three fungi with different types of transformation of glycyrrhizin (GL) were isolated from the soil samples of glycyrrhiza glabra planting area in China. According to their morphologies and 18 S rDNA gene sequence analysis, the three fungi were identified and named as Penicillium purpurogenum Li-3, Aspergillus terreus Li-20 and Aspergillus ustus Li-62. Transforming products analysis by TLC and HPLC-MS indicated that P. purpurogenum Li-3, A. terreus Li-20 and A. ustus Li-62 could stably transform GL into GAMG, GAMG and GA, and GA, respectively. P. purpurogenum Li-3 was especially valuable to directly prepare GAMG for applications in the pharmaceutical industry.

源语言	英语
页（从-至）	781-788
页数	8
期刊	World Journal of Microbiology and Biotechnology
卷	29
期	5
DOI	https://doi.org/10.1007/s11274-012-1233-9
出版状态	已出版 - 5月 2013

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@article{b6120c20d94840a7acea28a2fb11ac19,

title = "Isolation and characterization of three fungi with the potential of transforming glycyrrhizin",

abstract = "Three fungi with different types of transformation of glycyrrhizin (GL) were isolated from the soil samples of glycyrrhiza glabra planting area in China. According to their morphologies and 18 S rDNA gene sequence analysis, the three fungi were identified and named as Penicillium purpurogenum Li-3, Aspergillus terreus Li-20 and Aspergillus ustus Li-62. Transforming products analysis by TLC and HPLC-MS indicated that P. purpurogenum Li-3, A. terreus Li-20 and A. ustus Li-62 could stably transform GL into GAMG, GAMG and GA, and GA, respectively. P. purpurogenum Li-3 was especially valuable to directly prepare GAMG for applications in the pharmaceutical industry.",

keywords = "Biotransformation, Characterization, Fungus, Glycyrrhizin",

author = "Chao Wang and Guo, \{Xiao Xiao\} and Wang, \{Xiao Yan\} and Feng Qi and Feng, \{Shi Jiang\} and Chun Li and Zhou, \{Xiao Hong\}",

year = "2013",

month = may,

doi = "10.1007/s11274-012-1233-9",

language = "English",

volume = "29",

pages = "781--788",

journal = "World Journal of Microbiology and Biotechnology",

issn = "0959-3993",

publisher = "Springer Science and Business Media B.V.",

number = "5",

}

TY - JOUR

T1 - Isolation and characterization of three fungi with the potential of transforming glycyrrhizin

AU - Wang, Chao

AU - Guo, Xiao Xiao

AU - Wang, Xiao Yan

AU - Qi, Feng

AU - Feng, Shi Jiang

AU - Li, Chun

AU - Zhou, Xiao Hong

PY - 2013/5

Y1 - 2013/5

N2 - Three fungi with different types of transformation of glycyrrhizin (GL) were isolated from the soil samples of glycyrrhiza glabra planting area in China. According to their morphologies and 18 S rDNA gene sequence analysis, the three fungi were identified and named as Penicillium purpurogenum Li-3, Aspergillus terreus Li-20 and Aspergillus ustus Li-62. Transforming products analysis by TLC and HPLC-MS indicated that P. purpurogenum Li-3, A. terreus Li-20 and A. ustus Li-62 could stably transform GL into GAMG, GAMG and GA, and GA, respectively. P. purpurogenum Li-3 was especially valuable to directly prepare GAMG for applications in the pharmaceutical industry.

AB - Three fungi with different types of transformation of glycyrrhizin (GL) were isolated from the soil samples of glycyrrhiza glabra planting area in China. According to their morphologies and 18 S rDNA gene sequence analysis, the three fungi were identified and named as Penicillium purpurogenum Li-3, Aspergillus terreus Li-20 and Aspergillus ustus Li-62. Transforming products analysis by TLC and HPLC-MS indicated that P. purpurogenum Li-3, A. terreus Li-20 and A. ustus Li-62 could stably transform GL into GAMG, GAMG and GA, and GA, respectively. P. purpurogenum Li-3 was especially valuable to directly prepare GAMG for applications in the pharmaceutical industry.

KW - Biotransformation

KW - Characterization

KW - Fungus

KW - Glycyrrhizin

UR - https://www.scopus.com/pages/publications/84875746065

U2 - 10.1007/s11274-012-1233-9

DO - 10.1007/s11274-012-1233-9

M3 - Article

AN - SCOPUS:84875746065

SN - 0959-3993

VL - 29

SP - 781

EP - 788

JO - World Journal of Microbiology and Biotechnology

JF - World Journal of Microbiology and Biotechnology

IS - 5

ER -

Isolation and characterization of three fungi with the potential of transforming glycyrrhizin

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