Gold 3D brush nanoelectrode ensembles with enlarged active area for the direct voltammetry of daunorubicin

3D gold brush nanoelectrode ensembles (BNEEs) consisted of gold nanowires 100 nm in diameter and 300 nm in length were fabricated by combining the technologies of template synthesis and controlled chemical etching of the membrane. The structure and morphology of the BNEEs was imaged by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The real active areas of BNEEs were found to be different when characterized by different redox species. The direct redox of daunorubicin (DNR) at the gold BNEEs exhibited absorption-controlled characteristics and high current activity. BNEEs are reliable and effective in DNR detection.