Dual-signal lateral flow assay using vancomycin-modified nanotags for rapid and sensitive detection ofStaphylococcus aureus

Shu Wang; Wanzhu Shen; Shuai Zheng; Zhigang Li; Chongwen Wang; Long Zhang; Yong Liu

doi:10.1039/d1ra01085a

Dual-signal lateral flow assay using vancomycin-modified nanotags for rapid and sensitive detection ofStaphylococcus aureus

Shu Wang, Wanzhu Shen, Shuai Zheng, Zhigang Li, Chongwen Wang^*, Long Zhang, Yong Liu

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17 引用（Scopus）

摘要

This paper reports a colorimetric-fluorescent dual-signal lateral flow assay (LFA) based on vancomycin (Van)-modified SiO₂-Au-QD tags for sensitive and quantitative detection ofStaphylococcus aureus(S. aureus). The combination of high-performance Van-tags and detection antibodies integrated into the LFA system produced assays with high sensitivity and specificity. The visualization limit of the colorimetric signal and the detection limit of the fluorescence signal of the proposed method forS. aureuscan reach 10⁴and 100 cells mL^-1, respectively.

源语言	英语
页（从-至）	13297-13303
页数	7
期刊	RSC Advances
卷	11
期	22
DOI	https://doi.org/10.1039/d1ra01085a
出版状态	已出版 - 9 4月 2021
已对外发布	是

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title = "Dual-signal lateral flow assay using vancomycin-modified nanotags for rapid and sensitive detection ofStaphylococcus aureus",

abstract = "This paper reports a colorimetric-fluorescent dual-signal lateral flow assay (LFA) based on vancomycin (Van)-modified SiO2-Au-QD tags for sensitive and quantitative detection ofStaphylococcus aureus(S. aureus). The combination of high-performance Van-tags and detection antibodies integrated into the LFA system produced assays with high sensitivity and specificity. The visualization limit of the colorimetric signal and the detection limit of the fluorescence signal of the proposed method forS. aureuscan reach 104and 100 cells mL-1, respectively.",

author = "Shu Wang and Wanzhu Shen and Shuai Zheng and Zhigang Li and Chongwen Wang and Long Zhang and Yong Liu",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2021.",

year = "2021",

month = apr,

day = "9",

doi = "10.1039/d1ra01085a",

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T1 - Dual-signal lateral flow assay using vancomycin-modified nanotags for rapid and sensitive detection ofStaphylococcus aureus

AU - Wang, Shu

AU - Shen, Wanzhu

AU - Zheng, Shuai

AU - Li, Zhigang

AU - Wang, Chongwen

AU - Zhang, Long

AU - Liu, Yong

PY - 2021/4/9

Y1 - 2021/4/9

N2 - This paper reports a colorimetric-fluorescent dual-signal lateral flow assay (LFA) based on vancomycin (Van)-modified SiO2-Au-QD tags for sensitive and quantitative detection ofStaphylococcus aureus(S. aureus). The combination of high-performance Van-tags and detection antibodies integrated into the LFA system produced assays with high sensitivity and specificity. The visualization limit of the colorimetric signal and the detection limit of the fluorescence signal of the proposed method forS. aureuscan reach 104and 100 cells mL-1, respectively.

AB - This paper reports a colorimetric-fluorescent dual-signal lateral flow assay (LFA) based on vancomycin (Van)-modified SiO2-Au-QD tags for sensitive and quantitative detection ofStaphylococcus aureus(S. aureus). The combination of high-performance Van-tags and detection antibodies integrated into the LFA system produced assays with high sensitivity and specificity. The visualization limit of the colorimetric signal and the detection limit of the fluorescence signal of the proposed method forS. aureuscan reach 104and 100 cells mL-1, respectively.

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U2 - 10.1039/d1ra01085a

DO - 10.1039/d1ra01085a

M3 - Article

AN - SCOPUS:85104270378

SN - 2046-2069

VL - 11

SP - 13297

EP - 13303

JO - RSC Advances

JF - RSC Advances

IS - 22

ER -

Dual-signal lateral flow assay using vancomycin-modified nanotags for rapid and sensitive detection ofStaphylococcus aureus

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