A green and facile approach for synthesis of nitro heteroaromatics in water

Xiu X. Zhao; Ji C. Zhang; Sheng H. Li; Qing P. Yang; Yu C. Li; Si P. Pang

doi:10.1021/op5000754

A green and facile approach for synthesis of nitro heteroaromatics in water

Xiu X. Zhao
, Ji C. Zhang
, Sheng H. Li^*
, Qing P. Yang
, Yu C. Li
, Si P. Pang

^*此作品的通讯作者

材料学院

Beijing Institute of Technology

科研成果: 期刊稿件 › 文章 › 同行评审

27 引用（Scopus）

摘要

A convenient and green method for the oxidation of nitrogen-rich heterocyclic amines to nitro-substituted heteroaromatics using potassium peroxymonosulfate (2KHSO₅·KHSO₄·K ₂SO₄, Oxone) in water was developed. This method has several advantages over previous methods: operational simplicity, safety, inexpensive reagents, the use of H₂O as the sole solvent, and mild conditions. The utility of the present oxidative system was demonstrated by the synthesis of the important energetic compounds 3,4,5-trinitro-1H-pyrazole (TNP) and 5-amino-3-nitro-1H-1,2,4-triazole (ANTA).

源语言	英语
页（从-至）	886-890
页数	5
期刊	Organic Process Research and Development
卷	18
期	7
DOI	https://doi.org/10.1021/op5000754
出版状态	已出版 - 18 7月 2014

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title = "A green and facile approach for synthesis of nitro heteroaromatics in water",

abstract = "A convenient and green method for the oxidation of nitrogen-rich heterocyclic amines to nitro-substituted heteroaromatics using potassium peroxymonosulfate (2KHSO5·KHSO4·K 2SO4, Oxone) in water was developed. This method has several advantages over previous methods: operational simplicity, safety, inexpensive reagents, the use of H2O as the sole solvent, and mild conditions. The utility of the present oxidative system was demonstrated by the synthesis of the important energetic compounds 3,4,5-trinitro-1H-pyrazole (TNP) and 5-amino-3-nitro-1H-1,2,4-triazole (ANTA).",

author = "Zhao, \{Xiu X.\} and Zhang, \{Ji C.\} and Li, \{Sheng H.\} and Yang, \{Qing P.\} and Li, \{Yu C.\} and Pang, \{Si P.\}",

year = "2014",

month = jul,

day = "18",

doi = "10.1021/op5000754",

language = "English",

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TY - JOUR

T1 - A green and facile approach for synthesis of nitro heteroaromatics in water

AU - Zhao, Xiu X.

AU - Zhang, Ji C.

AU - Li, Sheng H.

AU - Yang, Qing P.

AU - Li, Yu C.

AU - Pang, Si P.

PY - 2014/7/18

Y1 - 2014/7/18

N2 - A convenient and green method for the oxidation of nitrogen-rich heterocyclic amines to nitro-substituted heteroaromatics using potassium peroxymonosulfate (2KHSO5·KHSO4·K 2SO4, Oxone) in water was developed. This method has several advantages over previous methods: operational simplicity, safety, inexpensive reagents, the use of H2O as the sole solvent, and mild conditions. The utility of the present oxidative system was demonstrated by the synthesis of the important energetic compounds 3,4,5-trinitro-1H-pyrazole (TNP) and 5-amino-3-nitro-1H-1,2,4-triazole (ANTA).

AB - A convenient and green method for the oxidation of nitrogen-rich heterocyclic amines to nitro-substituted heteroaromatics using potassium peroxymonosulfate (2KHSO5·KHSO4·K 2SO4, Oxone) in water was developed. This method has several advantages over previous methods: operational simplicity, safety, inexpensive reagents, the use of H2O as the sole solvent, and mild conditions. The utility of the present oxidative system was demonstrated by the synthesis of the important energetic compounds 3,4,5-trinitro-1H-pyrazole (TNP) and 5-amino-3-nitro-1H-1,2,4-triazole (ANTA).

UR - https://www.scopus.com/pages/publications/84904566402

U2 - 10.1021/op5000754

DO - 10.1021/op5000754

M3 - Article

AN - SCOPUS:84904566402

SN - 1083-6160

VL - 18

SP - 886

EP - 890

JO - Organic Process Research and Development

JF - Organic Process Research and Development

IS - 7

ER -

A green and facile approach for synthesis of nitro heteroaromatics in water

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