A colorimetric and ratiometric fluorescent probe for thiols and its bioimaging applications

Baocun Zhu; Xiaoling Zhang; Yamin Li; Pengfei Wang; Hongyan Zhang; Xiaoqing Zhuang

doi:10.1039/c0cc00477d

A colorimetric and ratiometric fluorescent probe for thiols and its bioimaging applications

Baocun Zhu
, Xiaoling Zhang^*
, Yamin Li
, Pengfei Wang
, Hongyan Zhang
, Xiaoqing Zhuang

^*此作品的通讯作者

化学与化工学院

Beijing Institute of Technology
CAS - Technical Institute of Physics and Chemistry

科研成果: 期刊稿件 › 文章 › 同行评审

211 引用（Scopus）

摘要

A naphthalimide-based colorimetric fluorescent probe containing a disulfide group was designed and synthesized, which could detect the physiological level of GSH quantitatively by a ratiometric fluorescence method and was successfully applied to the imaging of thiols in living HeLa cells.

源语言	英语
页（从-至）	5710-5712
页数	3
期刊	Chemical Communications
卷	46
期	31
DOI	https://doi.org/10.1039/c0cc00477d
出版状态	已出版 - 21 8月 2010

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title = "A colorimetric and ratiometric fluorescent probe for thiols and its bioimaging applications",

abstract = "A naphthalimide-based colorimetric fluorescent probe containing a disulfide group was designed and synthesized, which could detect the physiological level of GSH quantitatively by a ratiometric fluorescence method and was successfully applied to the imaging of thiols in living HeLa cells.",

author = "Baocun Zhu and Xiaoling Zhang and Yamin Li and Pengfei Wang and Hongyan Zhang and Xiaoqing Zhuang",

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T1 - A colorimetric and ratiometric fluorescent probe for thiols and its bioimaging applications

AU - Zhu, Baocun

AU - Zhang, Xiaoling

AU - Li, Yamin

AU - Wang, Pengfei

AU - Zhang, Hongyan

AU - Zhuang, Xiaoqing

PY - 2010/8/21

Y1 - 2010/8/21

N2 - A naphthalimide-based colorimetric fluorescent probe containing a disulfide group was designed and synthesized, which could detect the physiological level of GSH quantitatively by a ratiometric fluorescence method and was successfully applied to the imaging of thiols in living HeLa cells.

AB - A naphthalimide-based colorimetric fluorescent probe containing a disulfide group was designed and synthesized, which could detect the physiological level of GSH quantitatively by a ratiometric fluorescence method and was successfully applied to the imaging of thiols in living HeLa cells.

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U2 - 10.1039/c0cc00477d

DO - 10.1039/c0cc00477d

M3 - Article

C2 - 20596554

AN - SCOPUS:77955224668

SN - 1359-7345

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JO - Chemical Communications

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A colorimetric and ratiometric fluorescent probe for thiols and its bioimaging applications

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