基于真实世界数据的莪术油注射液临床用药特征分析

Objective; To analyze the clinical medication characteristics of zedoary turmeric oil injection based on real world data, and to provide reference for its clinical rational medication. Methods; Based on the data of 894 cases treated with zedoary turmeric oil injection extracted from the HIS system of 12 hospitals in China, the general data and medication status of the patients were described and analyzed by using frequency analysis method. The visual correlation analysis of the original diseases and combined medication status of 894 patients was carried out by using VOSviewer software and python program. Results; Among 894 patients who were administered zedoary turmeric oil injection, the frequency of upper respiratory tract infection was the highest, and the overall effective rate of treatment was 99. 55% . Among the 894 cases, 11. 52% were over the prescribed dropping rate, and 3 cases of adverse reactions were reported. In the aspect of combined use of zedoary turmeric oil injection, the solvent is mainly 5% glucose injection (73.60% ), and it is mostly combined with Reduning injection and ambroxol hydrochloride injection. Conclusion; zedoary turmeric oil injection has important application value in the treatment of respiratory and digestive system-related diseases. However, there are occasional mild adverse events, which may be related to the non-standard infusion operation. The existing data is limited, and the effectiveness and safety of zedoary turmeric oil injection in clinical application still need to be further improved. The reevaluation of the effectiveness and safety of traditional Chinese medicine injection should be strengthened after being listed. Also, higher quality evidence support should be provided for the clinical rational use of traditional Chinese medicine injection such as zedoary turmeric oil injection.