光电镊— 一种用途广泛的微纳操作工具

OptoElectronic Tweezer (OET) is a micro-scale optical manipulation technology based on photoinduced electrophoretic effect. It can accurately control small targets in the complex environment of fluid field, photoelectric field and biological force field, and has important applications to cell operation, micromechanical system and other fields. Optoelectronic tweezers technology can be used alone or in conjunction with other technologies, and has been widely used. To date, research based on optoelectronic tweezers has focused on manipulation, assembly, and synthesis of micro and nanomaterials; manipulation, isolation, and analysis of individual cells/molecules; analysis and acquisition of cell intrinsic properties; electroporation, fusion, and lysis of cells; preparation of cell-encapsulated biomaterials and biological structures; development of optical fluid devices for fluid transport. These works demonstrate the superior performance and unique versatility and flexibility of the optoelectronic tweezers technology. The existing application of optoelectronic tweezers technology are systematically presented in the paper and the application prospect, limitation and development trend of this technology are summarised.