The HPLC analysis of erythromycin 9-oxime

Jing Yu Wang; Ai Qin Luo; Yu Lin Deng; Jun Ling Gu; Wen Ma

The HPLC analysis of erythromycin 9-oxime

Jing Yu Wang^*, Ai Qin Luo, Yu Lin Deng, Jun Ling Gu, Wen Ma

^*Corresponding author for this work

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

Abstract

High performance liquid chromatography (HPLC) has been widely used in the quantitative analysis of erythromycin 9-oxime, an important intermediate for the synthesis of new erythromycin derivatives. HPLC method is used to analyse the content of erythromycin 9-oxime, and the stability of the method is evaluated. The results show that this method has a good stability and high accuracy. External method is applied, with the following chromatographic conditions: description of column: Nova-pak C₁₈, eluent used: V(CH ₃CN): V (0.033 mol/L KH₂PO₄) = (30: 70), detection wavelength; 205 nm, detection sensitity 0.1AUFS.

Original language	English
Pages (from-to)	771-773
Number of pages	3
Journal	He Jishu/Nuclear Techniques
Volume	22
Issue number	6
Publication status	Published - 1999

Keywords

Erythromycin 9-oxime
High performance liquid chromatography
Quantitative analysis
Stability

Cite this

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title = "The HPLC analysis of erythromycin 9-oxime",

abstract = "High performance liquid chromatography (HPLC) has been widely used in the quantitative analysis of erythromycin 9-oxime, an important intermediate for the synthesis of new erythromycin derivatives. HPLC method is used to analyse the content of erythromycin 9-oxime, and the stability of the method is evaluated. The results show that this method has a good stability and high accuracy. External method is applied, with the following chromatographic conditions: description of column: Nova-pak C18, eluent used: V(CH 3CN): V (0.033 mol/L KH2PO4) = (30: 70), detection wavelength; 205 nm, detection sensitity 0.1AUFS.",

keywords = "Erythromycin 9-oxime, High performance liquid chromatography, Quantitative analysis, Stability",

author = "Wang, \{Jing Yu\} and Luo, \{Ai Qin\} and Deng, \{Yu Lin\} and Gu, \{Jun Ling\} and Wen Ma",

year = "1999",

language = "English",

volume = "22",

pages = "771--773",

journal = "He Jishu/Nuclear Techniques",

issn = "0253-3219",

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TY - JOUR

T1 - The HPLC analysis of erythromycin 9-oxime

AU - Wang, Jing Yu

AU - Luo, Ai Qin

AU - Deng, Yu Lin

AU - Gu, Jun Ling

AU - Ma, Wen

PY - 1999

Y1 - 1999

N2 - High performance liquid chromatography (HPLC) has been widely used in the quantitative analysis of erythromycin 9-oxime, an important intermediate for the synthesis of new erythromycin derivatives. HPLC method is used to analyse the content of erythromycin 9-oxime, and the stability of the method is evaluated. The results show that this method has a good stability and high accuracy. External method is applied, with the following chromatographic conditions: description of column: Nova-pak C18, eluent used: V(CH 3CN): V (0.033 mol/L KH2PO4) = (30: 70), detection wavelength; 205 nm, detection sensitity 0.1AUFS.

AB - High performance liquid chromatography (HPLC) has been widely used in the quantitative analysis of erythromycin 9-oxime, an important intermediate for the synthesis of new erythromycin derivatives. HPLC method is used to analyse the content of erythromycin 9-oxime, and the stability of the method is evaluated. The results show that this method has a good stability and high accuracy. External method is applied, with the following chromatographic conditions: description of column: Nova-pak C18, eluent used: V(CH 3CN): V (0.033 mol/L KH2PO4) = (30: 70), detection wavelength; 205 nm, detection sensitity 0.1AUFS.

KW - Erythromycin 9-oxime

KW - High performance liquid chromatography

KW - Quantitative analysis

KW - Stability

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M3 - Article

AN - SCOPUS:77449091248

SN - 0253-3219

VL - 22

SP - 771

EP - 773

JO - He Jishu/Nuclear Techniques

JF - He Jishu/Nuclear Techniques

IS - 6

ER -

The HPLC analysis of erythromycin 9-oxime

Abstract

Keywords

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