Synthesis of novel C2-symmetric chiral bis(oxazoline) ligands and their application in the enantioselective addition of diethylzinc to aldehydes

Bin Fu; Da Ming Du; Jianbo Wang

doi:10.1016/j.tetasy.2003.11.006

Synthesis of novel C₂-symmetric chiral bis(oxazoline) ligands and their application in the enantioselective addition of diethylzinc to aldehydes

Bin Fu, Da Ming Du^*, Jianbo Wang

^*Corresponding author for this work

Peking University

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Abstract

Novel chiral bis(oxazoline) ligands bearing dibenzo[a,c]cycloheptadiene and a dihydroxy group have been synthesized and their application in the catalytic asymmetric addition of diethylzinc to aldehydes investigated. The enantioselectivities for the aromatic aldehydes are generally high and up to 96% ee was obtained.

Original language	English
Pages (from-to)	119-126
Number of pages	8
Journal	Tetrahedron Asymmetry
Volume	15
Issue number	1
DOIs	https://doi.org/10.1016/j.tetasy.2003.11.006
Publication status	Published - 12 Jan 2004
Externally published	Yes

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10.1016/j.tetasy.2003.11.006

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title = "Synthesis of novel C2-symmetric chiral bis(oxazoline) ligands and their application in the enantioselective addition of diethylzinc to aldehydes",

abstract = "Novel chiral bis(oxazoline) ligands bearing dibenzo[a,c]cycloheptadiene and a dihydroxy group have been synthesized and their application in the catalytic asymmetric addition of diethylzinc to aldehydes investigated. The enantioselectivities for the aromatic aldehydes are generally high and up to 96\% ee was obtained.",

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AU - Fu, Bin

AU - Du, Da Ming

AU - Wang, Jianbo

PY - 2004/1/12

Y1 - 2004/1/12

N2 - Novel chiral bis(oxazoline) ligands bearing dibenzo[a,c]cycloheptadiene and a dihydroxy group have been synthesized and their application in the catalytic asymmetric addition of diethylzinc to aldehydes investigated. The enantioselectivities for the aromatic aldehydes are generally high and up to 96% ee was obtained.

AB - Novel chiral bis(oxazoline) ligands bearing dibenzo[a,c]cycloheptadiene and a dihydroxy group have been synthesized and their application in the catalytic asymmetric addition of diethylzinc to aldehydes investigated. The enantioselectivities for the aromatic aldehydes are generally high and up to 96% ee was obtained.

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U2 - 10.1016/j.tetasy.2003.11.006

DO - 10.1016/j.tetasy.2003.11.006

M3 - Article

AN - SCOPUS:0347418209

SN - 0957-4166

VL - 15

SP - 119

EP - 126

JO - Tetrahedron Asymmetry

JF - Tetrahedron Asymmetry

IS - 1

ER -

Synthesis of novel C₂-symmetric chiral bis(oxazoline) ligands and their application in the enantioselective addition of diethylzinc to aldehydes

Abstract

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