Synthesis of NH-aziridines from vicinal amino alcohols via the Wenker reaction: Scope and limitation

Min Zhu; Libo Hu; Ning Chen; Da Ming Du; Jiaxi Xu

doi:10.2174/157017808783955844

Synthesis of NH-aziridines from vicinal amino alcohols via the Wenker reaction: Scope and limitation

Min Zhu, Libo Hu, Ning Chen, Da Ming Du, Jiaxi Xu^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

The Wenker reaction is an efficient and practical method for the synthesis of NH-aziridines from vicinal amino alcohols. However, some limitation in the application has been reported. The scope and limitation of the Wenker reaction were investigated with a series of structurally diverse and representative vicinal amino alcohols.

Original language	English
Pages (from-to)	212-217
Number of pages	6
Journal	Letters in Organic Chemistry
Volume	5
Issue number	3
DOIs	https://doi.org/10.2174/157017808783955844
Publication status	Published - 2008
Externally published	Yes

Keywords

Amino alcohol
Aziridine
Cyclization
Heterocyclic compound
Synthesis
Wenker reaction

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10.2174/157017808783955844

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title = "Synthesis of NH-aziridines from vicinal amino alcohols via the Wenker reaction: Scope and limitation",

abstract = "The Wenker reaction is an efficient and practical method for the synthesis of NH-aziridines from vicinal amino alcohols. However, some limitation in the application has been reported. The scope and limitation of the Wenker reaction were investigated with a series of structurally diverse and representative vicinal amino alcohols.",

keywords = "Amino alcohol, Aziridine, Cyclization, Heterocyclic compound, Synthesis, Wenker reaction",

author = "Min Zhu and Libo Hu and Ning Chen and Du, \{Da Ming\} and Jiaxi Xu",

year = "2008",

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language = "English",

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journal = "Letters in Organic Chemistry",

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TY - JOUR

T1 - Synthesis of NH-aziridines from vicinal amino alcohols via the Wenker reaction

T2 - Scope and limitation

AU - Zhu, Min

AU - Hu, Libo

AU - Chen, Ning

AU - Du, Da Ming

AU - Xu, Jiaxi

PY - 2008

Y1 - 2008

N2 - The Wenker reaction is an efficient and practical method for the synthesis of NH-aziridines from vicinal amino alcohols. However, some limitation in the application has been reported. The scope and limitation of the Wenker reaction were investigated with a series of structurally diverse and representative vicinal amino alcohols.

AB - The Wenker reaction is an efficient and practical method for the synthesis of NH-aziridines from vicinal amino alcohols. However, some limitation in the application has been reported. The scope and limitation of the Wenker reaction were investigated with a series of structurally diverse and representative vicinal amino alcohols.

KW - Amino alcohol

KW - Aziridine

KW - Cyclization

KW - Heterocyclic compound

KW - Synthesis

KW - Wenker reaction

UR - http://www.scopus.com/inward/record.url?scp=50149122004&partnerID=8YFLogxK

U2 - 10.2174/157017808783955844

DO - 10.2174/157017808783955844

M3 - Article

AN - SCOPUS:50149122004

SN - 1570-1786

VL - 5

SP - 212

EP - 217

JO - Letters in Organic Chemistry

JF - Letters in Organic Chemistry

IS - 3

ER -

Synthesis of NH-aziridines from vicinal amino alcohols via the Wenker reaction: Scope and limitation

Abstract

Keywords

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