Synthesis of MoS2 nanosheets drug delivery system and its drug release behaviors

Feng Wang; Fang Yuan Lv; Kui Long Liu; Zhi Hao Li; Shu Niu; Yun Yi Zhang; Hai Lin Cong; You Qing Shen; Bing Yu

doi:10.1080/00150193.2021.1902761

Synthesis of MoS₂ nanosheets drug delivery system and its drug release behaviors

Feng Wang
, Fang Yuan Lv
, Kui Long Liu
, Zhi Hao Li
, Shu Niu
, Yun Yi Zhang
, Hai Lin Cong
, You Qing Shen
, Bing Yu^*

^*Corresponding author for this work

Qingdao University

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

A MoS₂ nanosheets drug delivery system with photothermal conversion ability was synthesized. The drug loading content of the synthesized was as high as 24.5%. The drug HCPT was modified by lipoic acid (LA) and connected onto MoS₂ nanosheets through S-Mo bond, which is more stable than physical adsorption. Due to the ester bond between HCPT and MoS₂ nanosheets, the drug delivery system could responsively release HCPT when exposed to esterase.

Original language	English
Pages (from-to)	31-39
Number of pages	9
Journal	Ferroelectrics
Volume	578
Issue number	1
DOIs	https://doi.org/10.1080/00150193.2021.1902761
Publication status	Published - 2021
Externally published	Yes

Keywords

MoS2 nanosheets
drug release
esterase-responsive
photothermal conversion

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10.1080/00150193.2021.1902761

Cite this

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title = "Synthesis of MoS2 nanosheets drug delivery system and its drug release behaviors",

abstract = "A MoS2 nanosheets drug delivery system with photothermal conversion ability was synthesized. The drug loading content of the synthesized was as high as 24.5\%. The drug HCPT was modified by lipoic acid (LA) and connected onto MoS2 nanosheets through S-Mo bond, which is more stable than physical adsorption. Due to the ester bond between HCPT and MoS2 nanosheets, the drug delivery system could responsively release HCPT when exposed to esterase.",

keywords = "MoS2 nanosheets, drug release, esterase-responsive, photothermal conversion",

author = "Feng Wang and Lv, \{Fang Yuan\} and Liu, \{Kui Long\} and Li, \{Zhi Hao\} and Shu Niu and Zhang, \{Yun Yi\} and Cong, \{Hai Lin\} and Shen, \{You Qing\} and Bing Yu",

note = "Publisher Copyright: {\textcopyright} 2021 Taylor \& Francis Group, LLC.",

year = "2021",

doi = "10.1080/00150193.2021.1902761",

language = "English",

volume = "578",

pages = "31--39",

journal = "Ferroelectrics",

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TY - JOUR

T1 - Synthesis of MoS2 nanosheets drug delivery system and its drug release behaviors

AU - Wang, Feng

AU - Lv, Fang Yuan

AU - Liu, Kui Long

AU - Li, Zhi Hao

AU - Niu, Shu

AU - Zhang, Yun Yi

AU - Cong, Hai Lin

AU - Shen, You Qing

AU - Yu, Bing

PY - 2021

Y1 - 2021

N2 - A MoS2 nanosheets drug delivery system with photothermal conversion ability was synthesized. The drug loading content of the synthesized was as high as 24.5%. The drug HCPT was modified by lipoic acid (LA) and connected onto MoS2 nanosheets through S-Mo bond, which is more stable than physical adsorption. Due to the ester bond between HCPT and MoS2 nanosheets, the drug delivery system could responsively release HCPT when exposed to esterase.

AB - A MoS2 nanosheets drug delivery system with photothermal conversion ability was synthesized. The drug loading content of the synthesized was as high as 24.5%. The drug HCPT was modified by lipoic acid (LA) and connected onto MoS2 nanosheets through S-Mo bond, which is more stable than physical adsorption. Due to the ester bond between HCPT and MoS2 nanosheets, the drug delivery system could responsively release HCPT when exposed to esterase.

KW - MoS2 nanosheets

KW - drug release

KW - esterase-responsive

KW - photothermal conversion

UR - https://www.scopus.com/pages/publications/85112667516

U2 - 10.1080/00150193.2021.1902761

DO - 10.1080/00150193.2021.1902761

M3 - Article

AN - SCOPUS:85112667516

SN - 0015-0193

VL - 578

SP - 31

EP - 39

JO - Ferroelectrics

JF - Ferroelectrics

IS - 1

ER -

Synthesis of MoS₂ nanosheets drug delivery system and its drug release behaviors

Abstract

Keywords

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