Synthesis of deuterium-labelled trantinterol

Hongliang Wen; Li Pan; Yingdan Zhang; Jiacheng Ma; Liqiong Qin; Maosheng Cheng

doi:10.1002/jlcr.1796

Synthesis of deuterium-labelled trantinterol

Hongliang Wen^*, Li Pan, Yingdan Zhang, Jiacheng Ma, Liqiong Qin, Maosheng Cheng

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Trantinterol, a selective β₂-adrenoceptor agonist, is currently in Phase II clinical trials for the treatment of asthma and bronchitis. The synthesis of deuterium-labelled trantinterol is described. The labelled trantinterol is used as an internal standard for the analysis and metabolic studies.

Original language	English
Pages (from-to)	779-781
Number of pages	3
Journal	Journal of Labelled Compounds and Radiopharmaceuticals
Volume	53
Issue number	13
DOIs	https://doi.org/10.1002/jlcr.1796
Publication status	Published - Nov 2010
Externally published	Yes

Keywords

deuterium
labelled
synthesis
trantinterol

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10.1002/jlcr.1796

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title = "Synthesis of deuterium-labelled trantinterol",

abstract = "Trantinterol, a selective β2-adrenoceptor agonist, is currently in Phase II clinical trials for the treatment of asthma and bronchitis. The synthesis of deuterium-labelled trantinterol is described. The labelled trantinterol is used as an internal standard for the analysis and metabolic studies.",

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author = "Hongliang Wen and Li Pan and Yingdan Zhang and Jiacheng Ma and Liqiong Qin and Maosheng Cheng",

year = "2010",

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doi = "10.1002/jlcr.1796",

language = "English",

volume = "53",

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journal = "Journal of Labelled Compounds and Radiopharmaceuticals",

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TY - JOUR

T1 - Synthesis of deuterium-labelled trantinterol

AU - Wen, Hongliang

AU - Pan, Li

AU - Zhang, Yingdan

AU - Ma, Jiacheng

AU - Qin, Liqiong

AU - Cheng, Maosheng

PY - 2010/11

Y1 - 2010/11

N2 - Trantinterol, a selective β2-adrenoceptor agonist, is currently in Phase II clinical trials for the treatment of asthma and bronchitis. The synthesis of deuterium-labelled trantinterol is described. The labelled trantinterol is used as an internal standard for the analysis and metabolic studies.

AB - Trantinterol, a selective β2-adrenoceptor agonist, is currently in Phase II clinical trials for the treatment of asthma and bronchitis. The synthesis of deuterium-labelled trantinterol is described. The labelled trantinterol is used as an internal standard for the analysis and metabolic studies.

KW - deuterium

KW - labelled

KW - synthesis

KW - trantinterol

UR - http://www.scopus.com/inward/record.url?scp=78650672652&partnerID=8YFLogxK

U2 - 10.1002/jlcr.1796

DO - 10.1002/jlcr.1796

M3 - Article

AN - SCOPUS:78650672652

SN - 0362-4803

VL - 53

SP - 779

EP - 781

JO - Journal of Labelled Compounds and Radiopharmaceuticals

JF - Journal of Labelled Compounds and Radiopharmaceuticals

IS - 13

ER -

Synthesis of deuterium-labelled trantinterol

Abstract

Keywords

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