Abstract
Two chiral stationary phases (BCDs and YBCDs) were prepared by bonding β-cyclodextrin derivative with α-Schiff base group from β-cyclodextrin monoaldehyde to the silica gel via 3-glyci-dyloxypropyltrimethoxysilane as a coupling agent. Using acetonitrile-TEAA as mobile phase, good enantiomeric resolutions were obtained for DL-aminoacide on BCDs and YBCDs, including Leucine, Threonine and Valine. It is also observed that the higher separation factor of threonine was at pH 7.11 for both of the column, and the optimal column temperatures of Leucine appeared at 30°C or 40°C, respectively for YBCDs and BCDs.
| Original language | English |
|---|---|
| Pages (from-to) | 1443-1445 |
| Number of pages | 3 |
| Journal | Kao Teng Hsueh Hsiao Hua Heush Hsueh Pao/ Chemical Journal of Chinese Universities |
| Volume | 26 |
| Issue number | 8 |
| Publication status | Published - Aug 2005 |
Keywords
- HPLC
- Schiff base
- β-Cyclodextrin