Synthesis of 8-pentyl-guanosine by direct glycosylation

Muhua Huang

doi:10.6023/cjoc201209019

Synthesis of 8-pentyl-guanosine by direct glycosylation

Muhua Huang^*

^*Corresponding author for this work

School of Material Science and Engineering

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

8-Pentyl-guanosine was prepared by direct glycosylation based on the easy access to 8-pentyl-guanine, which provided a green chemistry approach to 8-C-substituted guanosine. In addition, this paper reported the isolation and characterization of an iminophosphane intermediate, which provide an experimental evidence for the proposed mechanism.

Original language	English
Pages (from-to)	106-109
Number of pages	4
Journal	Chinese Journal of Organic Chemistry
Volume	33
Issue number	1
DOIs	https://doi.org/10.6023/cjoc201209019
Publication status	Published - Jan 2013

Keywords

8-alkyl-guanine
Direct glycosylation
Iminophosphane
Nitrosopyrimdine
Nucleoside

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10.6023/cjoc201209019

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title = "Synthesis of 8-pentyl-guanosine by direct glycosylation",

abstract = "8-Pentyl-guanosine was prepared by direct glycosylation based on the easy access to 8-pentyl-guanine, which provided a green chemistry approach to 8-C-substituted guanosine. In addition, this paper reported the isolation and characterization of an iminophosphane intermediate, which provide an experimental evidence for the proposed mechanism.",

keywords = "8-alkyl-guanine, Direct glycosylation, Iminophosphane, Nitrosopyrimdine, Nucleoside",

author = "Muhua Huang",

year = "2013",

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T1 - Synthesis of 8-pentyl-guanosine by direct glycosylation

AU - Huang, Muhua

PY - 2013/1

Y1 - 2013/1

N2 - 8-Pentyl-guanosine was prepared by direct glycosylation based on the easy access to 8-pentyl-guanine, which provided a green chemistry approach to 8-C-substituted guanosine. In addition, this paper reported the isolation and characterization of an iminophosphane intermediate, which provide an experimental evidence for the proposed mechanism.

AB - 8-Pentyl-guanosine was prepared by direct glycosylation based on the easy access to 8-pentyl-guanine, which provided a green chemistry approach to 8-C-substituted guanosine. In addition, this paper reported the isolation and characterization of an iminophosphane intermediate, which provide an experimental evidence for the proposed mechanism.

KW - 8-alkyl-guanine

KW - Direct glycosylation

KW - Iminophosphane

KW - Nitrosopyrimdine

KW - Nucleoside

UR - https://www.scopus.com/pages/publications/84876300943

U2 - 10.6023/cjoc201209019

DO - 10.6023/cjoc201209019

M3 - Article

AN - SCOPUS:84876300943

SN - 0253-2786

VL - 33

SP - 106

EP - 109

JO - Chinese Journal of Organic Chemistry

JF - Chinese Journal of Organic Chemistry

IS - 1

ER -

Synthesis of 8-pentyl-guanosine by direct glycosylation

Abstract

Keywords

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