Synthesis of 2-methoxy-3, 5-dinitryl-6-azidepyrazine

Yao Peng Liu; Hua Xiong Chen; Shu Sen Chen; Shao Hua Jin

Synthesis of 2-methoxy-3, 5-dinitryl-6-azidepyrazine

Yao Peng Liu^*, Hua Xiong Chen, Shu Sen Chen, Shao Hua Jin

^*Corresponding author for this work

School of Material Science and Engineering

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

MDNAP is a precursor for novel energetic compounds. 2-methoxy-6-chlorin pyrazine (MCP) was first synthesized from raw material 2, 6-dichlorin pyrazine by substituting chlorine with methoxyl with a yield of 81%. 2-methoxy-3, 5-dinitryl-6-chlorin pyrazine (MDNCP) was obtained by the nitration of MCP with mixed nitric and sulfuric acids under facile conditions with a yield of 75%.2-methoxy-3, 5-dinitryl-6-azide pyrazine (MDNAP) was synthesized from MDNCP by the zaide substitution of MDNCP with a yield of 60%. Therein, all the intermediates were characterized by IR, H¹ NMR, ESI-MS and EI-MS.

Original language	English
Pages (from-to)	1357-1362
Number of pages	6
Journal	Binggong Xuebao/Acta Armamentarii
Volume	31
Issue number	10
Publication status	Published - Oct 2010

Keywords

2-methoxy-3, 5-dinitryl-6-azidepyrazine
Azide substitution
Nitration
Organic chemistry
Pyrazine

Cite this

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title = "Synthesis of 2-methoxy-3, 5-dinitryl-6-azidepyrazine",

abstract = "MDNAP is a precursor for novel energetic compounds. 2-methoxy-6-chlorin pyrazine (MCP) was first synthesized from raw material 2, 6-dichlorin pyrazine by substituting chlorine with methoxyl with a yield of 81%. 2-methoxy-3, 5-dinitryl-6-chlorin pyrazine (MDNCP) was obtained by the nitration of MCP with mixed nitric and sulfuric acids under facile conditions with a yield of 75%.2-methoxy-3, 5-dinitryl-6-azide pyrazine (MDNAP) was synthesized from MDNCP by the zaide substitution of MDNCP with a yield of 60%. Therein, all the intermediates were characterized by IR, H1 NMR, ESI-MS and EI-MS.",

keywords = "2-methoxy-3, 5-dinitryl-6-azidepyrazine, Azide substitution, Nitration, Organic chemistry, Pyrazine",

author = "Liu, {Yao Peng} and Chen, {Hua Xiong} and Chen, {Shu Sen} and Jin, {Shao Hua}",

year = "2010",

month = oct,

language = "English",

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journal = "Binggong Xuebao/Acta Armamentarii",

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T1 - Synthesis of 2-methoxy-3, 5-dinitryl-6-azidepyrazine

AU - Liu, Yao Peng

AU - Chen, Hua Xiong

AU - Chen, Shu Sen

AU - Jin, Shao Hua

PY - 2010/10

Y1 - 2010/10

N2 - MDNAP is a precursor for novel energetic compounds. 2-methoxy-6-chlorin pyrazine (MCP) was first synthesized from raw material 2, 6-dichlorin pyrazine by substituting chlorine with methoxyl with a yield of 81%. 2-methoxy-3, 5-dinitryl-6-chlorin pyrazine (MDNCP) was obtained by the nitration of MCP with mixed nitric and sulfuric acids under facile conditions with a yield of 75%.2-methoxy-3, 5-dinitryl-6-azide pyrazine (MDNAP) was synthesized from MDNCP by the zaide substitution of MDNCP with a yield of 60%. Therein, all the intermediates were characterized by IR, H1 NMR, ESI-MS and EI-MS.

AB - MDNAP is a precursor for novel energetic compounds. 2-methoxy-6-chlorin pyrazine (MCP) was first synthesized from raw material 2, 6-dichlorin pyrazine by substituting chlorine with methoxyl with a yield of 81%. 2-methoxy-3, 5-dinitryl-6-chlorin pyrazine (MDNCP) was obtained by the nitration of MCP with mixed nitric and sulfuric acids under facile conditions with a yield of 75%.2-methoxy-3, 5-dinitryl-6-azide pyrazine (MDNAP) was synthesized from MDNCP by the zaide substitution of MDNCP with a yield of 60%. Therein, all the intermediates were characterized by IR, H1 NMR, ESI-MS and EI-MS.

KW - 2-methoxy-3, 5-dinitryl-6-azidepyrazine

KW - Azide substitution

KW - Nitration

KW - Organic chemistry

KW - Pyrazine

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M3 - Article

AN - SCOPUS:78650011229

SN - 1000-1093

VL - 31

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EP - 1362

JO - Binggong Xuebao/Acta Armamentarii

JF - Binggong Xuebao/Acta Armamentarii

IS - 10

ER -

Synthesis of 2-methoxy-3, 5-dinitryl-6-azidepyrazine

Abstract

Keywords

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