Synthesis of 2, 3, 8, 9-Tetrahydropyrido [2, 3-d: 6, 5-d'] dipyrimidine-4, 6-diones

Liupan Yang; Jiarong Li; Hongxin Chai; Hong Yuan; Qi Zhang; Daxin Shi

doi:10.6023/cjoc201208039

Synthesis of 2, 3, 8, 9-Tetrahydropyrido [2, 3-d: 6, 5-d'] dipyrimidine-4, 6-diones

Liupan Yang^*
, Jiarong Li
, Hongxin Chai
, Hong Yuan
, Qi Zhang
, Daxin Shi

^*Corresponding author for this work

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

2, 3, 8, 9-Tetrahydropyrido [2, 3-d: 6, 5-d'] dipyrimidine-4, 6-diones were synthesized by using malononitrile, ortho-triethyl and pyridine as starting materials in three steps reaction including cyclization, ammonolysis and reaction with ketones under the catalysis of sodium methoxide. The structures of the products were confirmed by NMR, IR, ESI and elemental analysis.

Original language	English
Pages (from-to)	174-177
Number of pages	4
Journal	Chinese Journal of Organic Chemistry
Volume	33
Issue number	1
DOIs	https://doi.org/10.6023/cjoc201208039
Publication status	Published - Jan 2013
Externally published	Yes

Keywords

Heterocycle
Pyridodipyrimidinediones
Synthesis

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10.6023/cjoc201208039

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title = "Synthesis of 2, 3, 8, 9-Tetrahydropyrido [2, 3-d: 6, 5-d'] dipyrimidine-4, 6-diones",

abstract = "2, 3, 8, 9-Tetrahydropyrido [2, 3-d: 6, 5-d'] dipyrimidine-4, 6-diones were synthesized by using malononitrile, ortho-triethyl and pyridine as starting materials in three steps reaction including cyclization, ammonolysis and reaction with ketones under the catalysis of sodium methoxide. The structures of the products were confirmed by NMR, IR, ESI and elemental analysis.",

keywords = "Heterocycle, Pyridodipyrimidinediones, Synthesis",

author = "Liupan Yang and Jiarong Li and Hongxin Chai and Hong Yuan and Qi Zhang and Daxin Shi",

year = "2013",

month = jan,

doi = "10.6023/cjoc201208039",

language = "English",

volume = "33",

pages = "174--177",

journal = "Chinese Journal of Organic Chemistry",

issn = "0253-2786",

publisher = "Science Press",

number = "1",

}

TY - JOUR

T1 - Synthesis of 2, 3, 8, 9-Tetrahydropyrido [2, 3-d

T2 - 6, 5-d'] dipyrimidine-4, 6-diones

AU - Yang, Liupan

AU - Li, Jiarong

AU - Chai, Hongxin

AU - Yuan, Hong

AU - Zhang, Qi

AU - Shi, Daxin

PY - 2013/1

Y1 - 2013/1

N2 - 2, 3, 8, 9-Tetrahydropyrido [2, 3-d: 6, 5-d'] dipyrimidine-4, 6-diones were synthesized by using malononitrile, ortho-triethyl and pyridine as starting materials in three steps reaction including cyclization, ammonolysis and reaction with ketones under the catalysis of sodium methoxide. The structures of the products were confirmed by NMR, IR, ESI and elemental analysis.

AB - 2, 3, 8, 9-Tetrahydropyrido [2, 3-d: 6, 5-d'] dipyrimidine-4, 6-diones were synthesized by using malononitrile, ortho-triethyl and pyridine as starting materials in three steps reaction including cyclization, ammonolysis and reaction with ketones under the catalysis of sodium methoxide. The structures of the products were confirmed by NMR, IR, ESI and elemental analysis.

KW - Heterocycle

KW - Pyridodipyrimidinediones

KW - Synthesis

UR - https://www.scopus.com/pages/publications/84876247952

U2 - 10.6023/cjoc201208039

DO - 10.6023/cjoc201208039

M3 - Article

AN - SCOPUS:84876247952

SN - 0253-2786

VL - 33

SP - 174

EP - 177

JO - Chinese Journal of Organic Chemistry

JF - Chinese Journal of Organic Chemistry

IS - 1

ER -

Synthesis of 2, 3, 8, 9-Tetrahydropyrido [2, 3-d: 6, 5-d'] dipyrimidine-4, 6-diones

Abstract

Keywords

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