Synthesis and crystal structure of (9s)-N-methyl-3-azabicyclo[3.3.1] nonan-9-yl (cyclopentyl)(hydroxy)(2-thienyl)acetate hydrochloride

Yan Qing Liu; He Liu; Bo Hua Zhong; Yu Lin Deng; Ke Liang Liu

doi:10.3184/030823405774309041

Synthesis and crystal structure of (9s)-N-methyl-3-azabicyclo[3.3.1] nonan-9-yl (cyclopentyl)(hydroxy)(2-thienyl)acetate hydrochloride

Yan Qing Liu
, He Liu^*
, Bo Hua Zhong
, Yu Lin Deng
, Ke Liang Liu

^*Corresponding author for this work

School of Medical Science and Engineering

Beijing Institute of Technology
Beijing Institute of Pharmacology and Toxicology

Research output: Contribution to journal › Article › peer-review

Abstract

(9s)-N-methyl-3-azabicyclo[3.3.1]nonan-9-yl (cyclopentyl)(hydroxy)(2- thienyl)acetate hydrochloride, a more effective muscarinic receptor antagonist, was synthesised and its crystal structure elucidated by X-ray crystallography.

Original language	English
Pages (from-to)	436-437
Number of pages	2
Journal	Journal of Chemical Research - Part S
Issue number	7
DOIs	https://doi.org/10.3184/030823405774309041
Publication status	Published - Jul 2005

Keywords

Crystal structure
Muscarinic receptor antagonist
Synthesis

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title = "Synthesis and crystal structure of (9s)-N-methyl-3-azabicyclo[3.3.1] nonan-9-yl (cyclopentyl)(hydroxy)(2-thienyl)acetate hydrochloride",

abstract = "(9s)-N-methyl-3-azabicyclo[3.3.1]nonan-9-yl (cyclopentyl)(hydroxy)(2- thienyl)acetate hydrochloride, a more effective muscarinic receptor antagonist, was synthesised and its crystal structure elucidated by X-ray crystallography.",

keywords = "Crystal structure, Muscarinic receptor antagonist, Synthesis",

author = "Liu, \{Yan Qing\} and He Liu and Zhong, \{Bo Hua\} and Deng, \{Yu Lin\} and Liu, \{Ke Liang\}",

year = "2005",

month = jul,

doi = "10.3184/030823405774309041",

language = "English",

pages = "436--437",

journal = "Journal of Chemical Research - Part S",

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publisher = "Scientific Reviews 2000 Ltd.",

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T1 - Synthesis and crystal structure of (9s)-N-methyl-3-azabicyclo[3.3.1] nonan-9-yl (cyclopentyl)(hydroxy)(2-thienyl)acetate hydrochloride

AU - Liu, Yan Qing

AU - Liu, He

AU - Zhong, Bo Hua

AU - Deng, Yu Lin

AU - Liu, Ke Liang

PY - 2005/7

Y1 - 2005/7

N2 - (9s)-N-methyl-3-azabicyclo[3.3.1]nonan-9-yl (cyclopentyl)(hydroxy)(2- thienyl)acetate hydrochloride, a more effective muscarinic receptor antagonist, was synthesised and its crystal structure elucidated by X-ray crystallography.

AB - (9s)-N-methyl-3-azabicyclo[3.3.1]nonan-9-yl (cyclopentyl)(hydroxy)(2- thienyl)acetate hydrochloride, a more effective muscarinic receptor antagonist, was synthesised and its crystal structure elucidated by X-ray crystallography.

KW - Crystal structure

KW - Muscarinic receptor antagonist

KW - Synthesis

UR - https://www.scopus.com/pages/publications/23344450037

U2 - 10.3184/030823405774309041

DO - 10.3184/030823405774309041

M3 - Article

AN - SCOPUS:23344450037

SN - 0308-2342

SP - 436

EP - 437

JO - Journal of Chemical Research - Part S

JF - Journal of Chemical Research - Part S

IS - 7

ER -

Synthesis and crystal structure of (9s)-N-methyl-3-azabicyclo[3.3.1] nonan-9-yl (cyclopentyl)(hydroxy)(2-thienyl)acetate hydrochloride

Abstract

Keywords

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