Abstract
A process was developed to prepare pH-sensitive guar gum/poly(acrylic acid) (GG/PAA) semi-interpenetrating polymer network hydrogels. The influence of feed composition and pH in the swelling medium on swelling dynamics was investigated. Results show: the maximum swelling ratio and diffusion exponent n of hydrogels decrease with the increase GG amount, but increase with enhanced AA amount and pH. The swelling processes follow Schott second order dynamic equation. GG/PAA semi-IPNs are expected to be good candidates for the carriers for colon-specific drug delivery system.
| Original language | English |
|---|---|
| Pages (from-to) | 177-180 |
| Number of pages | 4 |
| Journal | Gaofenzi Cailiao Kexue Yu Gongcheng/Polymeric Materials Science and Engineering |
| Volume | 22 |
| Issue number | 2 |
| Publication status | Published - Mar 2006 |
Keywords
- Guar gum
- Hydrogels
- Poly(acrylic acid)
- Swelling dynamics
- pH-sensitive
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