Study on the chiral separation of anisodamine by high performance capillary electrophoresis

Hong Wang; Junling Gu; Rongji Dai; Ruonong Fu; Hanfang Hu; Tianhui Ding

Study on the chiral separation of anisodamine by high performance capillary electrophoresis

Hong Wang^*
, Junling Gu
, Rongji Dai
, Ruonong Fu
, Hanfang Hu
, Tianhui Ding

^*Corresponding author for this work

School of Life Science

Beijing Institute of Technology
Hebei University

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Aim: To study the enantiomeric separation of anisodamine. Methods: The factors influencing complexation and resolution were investigated using ß-cyclodextrin (ß-CD) and 2, 6-di-O-carboxymethyl-ß- cyclodextrin (CM-ß-CD) as the chiral selectors by high performance capillary electrophoresis (HPCE). Results: The optimum chiral separation system for anisodamine was established. Conclusion: CM-ß-CD can give a baseline chiral separation for anisodamine and no resolution is found for scopolamine or atropine.

Original language	English
Pages (from-to)	380-384
Number of pages	5
Journal	Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology
Volume	18
Issue number	3
Publication status	Published - 1998

Keywords

Anisodamine
Chiral separation
High performance capillary electrophoresis
ß-CDs

Cite this

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title = "Study on the chiral separation of anisodamine by high performance capillary electrophoresis",

abstract = "Aim: To study the enantiomeric separation of anisodamine. Methods: The factors influencing complexation and resolution were investigated using {\ss}-cyclodextrin ({\ss}-CD) and 2, 6-di-O-carboxymethyl-{\ss}- cyclodextrin (CM-{\ss}-CD) as the chiral selectors by high performance capillary electrophoresis (HPCE). Results: The optimum chiral separation system for anisodamine was established. Conclusion: CM-{\ss}-CD can give a baseline chiral separation for anisodamine and no resolution is found for scopolamine or atropine.",

keywords = "Anisodamine, Chiral separation, High performance capillary electrophoresis, {\ss}-CDs",

author = "Hong Wang and Junling Gu and Rongji Dai and Ruonong Fu and Hanfang Hu and Tianhui Ding",

year = "1998",

language = "English",

volume = "18",

pages = "380--384",

journal = "Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology",

issn = "1001-0645",

publisher = "Beijing Institute of Technology",

number = "3",

}

TY - JOUR

T1 - Study on the chiral separation of anisodamine by high performance capillary electrophoresis

AU - Wang, Hong

AU - Gu, Junling

AU - Dai, Rongji

AU - Fu, Ruonong

AU - Hu, Hanfang

AU - Ding, Tianhui

PY - 1998

Y1 - 1998

N2 - Aim: To study the enantiomeric separation of anisodamine. Methods: The factors influencing complexation and resolution were investigated using ß-cyclodextrin (ß-CD) and 2, 6-di-O-carboxymethyl-ß- cyclodextrin (CM-ß-CD) as the chiral selectors by high performance capillary electrophoresis (HPCE). Results: The optimum chiral separation system for anisodamine was established. Conclusion: CM-ß-CD can give a baseline chiral separation for anisodamine and no resolution is found for scopolamine or atropine.

AB - Aim: To study the enantiomeric separation of anisodamine. Methods: The factors influencing complexation and resolution were investigated using ß-cyclodextrin (ß-CD) and 2, 6-di-O-carboxymethyl-ß- cyclodextrin (CM-ß-CD) as the chiral selectors by high performance capillary electrophoresis (HPCE). Results: The optimum chiral separation system for anisodamine was established. Conclusion: CM-ß-CD can give a baseline chiral separation for anisodamine and no resolution is found for scopolamine or atropine.

KW - Anisodamine

KW - Chiral separation

KW - High performance capillary electrophoresis

KW - ß-CDs

UR - https://www.scopus.com/pages/publications/20444405138

M3 - Article

AN - SCOPUS:20444405138

SN - 1001-0645

VL - 18

SP - 380

EP - 384

JO - Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology

JF - Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology

IS - 3

ER -

Study on the chiral separation of anisodamine by high performance capillary electrophoresis

Abstract

Keywords

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