Structurally Well-Defined Au@Cu2-xS Core-Shell Nanocrystals for Improved Cancer Treatment Based on Enhanced Photothermal Efficiency

Muwei Ji; Meng Xu; Wei Zhang; Zhenzhong Yang; Liu Huang; Jiajia Liu; Yong Zhang; Lin Gu; Youxing Yu; Weichang Hao; Pengfei An; Lirong Zheng; Hesun Zhu; Jiatao Zhang

doi:10.1002/adma.201503201

Structurally Well-Defined Au@Cu_2-_xS Core-Shell Nanocrystals for Improved Cancer Treatment Based on Enhanced Photothermal Efficiency

Muwei Ji, Meng Xu, Wei Zhang, Zhenzhong Yang, Liu Huang, Jiajia Liu, Yong Zhang, Lin Gu, Youxing Yu, Weichang Hao, Pengfei An, Lirong Zheng, Hesun Zhu, Jiatao Zhang^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

251 Citations (Scopus)

Abstract

Au@Cu_2-_xS core-shell nanocrystals (NCs) have been synthesized under large lattice mismatch with high crystallinity, controllable shape, and nonstoichiometric composition. Both experimental observations and simulations are used to verify the flexible dual-mode plasmon coupling. The enhanced photothermal effect is harnessed for diverse HeLa cancer cell ablation applications in the NIR-I window (750-900 nm) and the NIR-II window (1000-1400 nm).

Original language	English
Pages (from-to)	3094-3101
Number of pages	8
Journal	Advanced Materials
Volume	28
Issue number	16
DOIs	https://doi.org/10.1002/adma.201503201
Publication status	Published - 27 Apr 2016

Keywords

Au@CuS core-shell nanocrystals
dual-mode plasmon coupling
in vivo cancer treatment
photothermal
surface plasmon resonance coupling

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/adma.201503201

Cite this

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title = "Structurally Well-Defined Au@Cu2-xS Core-Shell Nanocrystals for Improved Cancer Treatment Based on Enhanced Photothermal Efficiency",

abstract = "Au@Cu2-xS core-shell nanocrystals (NCs) have been synthesized under large lattice mismatch with high crystallinity, controllable shape, and nonstoichiometric composition. Both experimental observations and simulations are used to verify the flexible dual-mode plasmon coupling. The enhanced photothermal effect is harnessed for diverse HeLa cancer cell ablation applications in the NIR-I window (750-900 nm) and the NIR-II window (1000-1400 nm).",

keywords = "Au@CuS core-shell nanocrystals, dual-mode plasmon coupling, in vivo cancer treatment, photothermal, surface plasmon resonance coupling",

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doi = "10.1002/adma.201503201",

language = "English",

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T1 - Structurally Well-Defined Au@Cu2-xS Core-Shell Nanocrystals for Improved Cancer Treatment Based on Enhanced Photothermal Efficiency

AU - Ji, Muwei

AU - Xu, Meng

AU - Zhang, Wei

AU - Yang, Zhenzhong

AU - Huang, Liu

AU - Liu, Jiajia

AU - Zhang, Yong

AU - Gu, Lin

AU - Yu, Youxing

AU - Hao, Weichang

AU - An, Pengfei

AU - Zheng, Lirong

AU - Zhu, Hesun

AU - Zhang, Jiatao

PY - 2016/4/27

Y1 - 2016/4/27

N2 - Au@Cu2-xS core-shell nanocrystals (NCs) have been synthesized under large lattice mismatch with high crystallinity, controllable shape, and nonstoichiometric composition. Both experimental observations and simulations are used to verify the flexible dual-mode plasmon coupling. The enhanced photothermal effect is harnessed for diverse HeLa cancer cell ablation applications in the NIR-I window (750-900 nm) and the NIR-II window (1000-1400 nm).

AB - Au@Cu2-xS core-shell nanocrystals (NCs) have been synthesized under large lattice mismatch with high crystallinity, controllable shape, and nonstoichiometric composition. Both experimental observations and simulations are used to verify the flexible dual-mode plasmon coupling. The enhanced photothermal effect is harnessed for diverse HeLa cancer cell ablation applications in the NIR-I window (750-900 nm) and the NIR-II window (1000-1400 nm).

KW - Au@CuS core-shell nanocrystals

KW - dual-mode plasmon coupling

KW - in vivo cancer treatment

KW - photothermal

KW - surface plasmon resonance coupling

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