Solvent-free, AlCl3-promoted tandem Friedel-Crafts reaction of arenes and aldehydes

Xiao Wang; Yikai Wang; Da Ming Du; Jiaxi Xu

doi:10.1016/j.molcata.2006.03.060

Solvent-free, AlCl₃-promoted tandem Friedel-Crafts reaction of arenes and aldehydes

Xiao Wang
, Yikai Wang
, Da Ming Du
, Jiaxi Xu^*

^*Corresponding author for this work

Ministry of Education in China

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

Tandem Friedel-Crafts reaction of arenes and aldehydes under the catalysis of Lewis acid was investigated. Both aromatic and aliphatic aldehydes underwent a tandem Friedel-Crafts alkylation with electron-rich arenes to afford 1,1,1-triaryl/1,1-diarylalkanes in the presence of anhydrous aluminum chloride under solvent-free conditions. The scope, limitation, and mechanism of the tandem reaction were also discussed.

Original language	English
Pages (from-to)	31-35
Number of pages	5
Journal	Journal of Molecular Catalysis A: Chemical
Volume	255
Issue number	1-2
DOIs	https://doi.org/10.1016/j.molcata.2006.03.060
Publication status	Published - 1 Aug 2006
Externally published	Yes

Keywords

Alcohol
Aldehyde
Aluminum chloride
Arene
Friedel-Crafts alkylation
Solvent-free
Tandem reaction

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10.1016/j.molcata.2006.03.060

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title = "Solvent-free, AlCl3-promoted tandem Friedel-Crafts reaction of arenes and aldehydes",

abstract = "Tandem Friedel-Crafts reaction of arenes and aldehydes under the catalysis of Lewis acid was investigated. Both aromatic and aliphatic aldehydes underwent a tandem Friedel-Crafts alkylation with electron-rich arenes to afford 1,1,1-triaryl/1,1-diarylalkanes in the presence of anhydrous aluminum chloride under solvent-free conditions. The scope, limitation, and mechanism of the tandem reaction were also discussed.",

keywords = "Alcohol, Aldehyde, Aluminum chloride, Arene, Friedel-Crafts alkylation, Solvent-free, Tandem reaction",

author = "Xiao Wang and Yikai Wang and Du, \{Da Ming\} and Jiaxi Xu",

year = "2006",

month = aug,

day = "1",

doi = "10.1016/j.molcata.2006.03.060",

language = "English",

volume = "255",

pages = "31--35",

journal = "Journal of Molecular Catalysis A: Chemical",

issn = "1381-1169",

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number = "1-2",

}

TY - JOUR

T1 - Solvent-free, AlCl3-promoted tandem Friedel-Crafts reaction of arenes and aldehydes

AU - Wang, Xiao

AU - Wang, Yikai

AU - Du, Da Ming

AU - Xu, Jiaxi

PY - 2006/8/1

Y1 - 2006/8/1

N2 - Tandem Friedel-Crafts reaction of arenes and aldehydes under the catalysis of Lewis acid was investigated. Both aromatic and aliphatic aldehydes underwent a tandem Friedel-Crafts alkylation with electron-rich arenes to afford 1,1,1-triaryl/1,1-diarylalkanes in the presence of anhydrous aluminum chloride under solvent-free conditions. The scope, limitation, and mechanism of the tandem reaction were also discussed.

AB - Tandem Friedel-Crafts reaction of arenes and aldehydes under the catalysis of Lewis acid was investigated. Both aromatic and aliphatic aldehydes underwent a tandem Friedel-Crafts alkylation with electron-rich arenes to afford 1,1,1-triaryl/1,1-diarylalkanes in the presence of anhydrous aluminum chloride under solvent-free conditions. The scope, limitation, and mechanism of the tandem reaction were also discussed.

KW - Alcohol

KW - Aldehyde

KW - Aluminum chloride

KW - Arene

KW - Friedel-Crafts alkylation

KW - Solvent-free

KW - Tandem reaction

UR - https://www.scopus.com/pages/publications/33745971431

U2 - 10.1016/j.molcata.2006.03.060

DO - 10.1016/j.molcata.2006.03.060

M3 - Article

AN - SCOPUS:33745971431

SN - 1381-1169

VL - 255

SP - 31

EP - 35

JO - Journal of Molecular Catalysis A: Chemical

JF - Journal of Molecular Catalysis A: Chemical

IS - 1-2

ER -

Solvent-free, AlCl₃-promoted tandem Friedel-Crafts reaction of arenes and aldehydes

Abstract

Keywords

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