Softness, anomalous dynamics, and fractal-like energy landscape in model cell tissues

Yan Wei Li, Leon Loh Yeong Wei, Matteo Paoluzzi, Massimo Pica Ciamarra*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

Epithelial cell tissues have a slow relaxation dynamics resembling that of supercooled liquids. Yet, they also have distinguishing features. These include an extended short-time subdiffusive transient, as observed in some experiments and recent studies of model systems, and a sub-Arrhenius dependence of the relaxation time on temperature, as reported in numerical studies. Here we demonstrate that the anomalous glassy dynamics of epithelial tissues originates from the emergence of a fractal-like energy landscape, particles becoming virtually free to diffuse in specific phase space directions up to a small distance. Furthermore, we clarify that the stiffness of the cells tunes this anomalous behavior, tissues of stiff cells having conventional glassy relaxation dynamics.

Original languageEnglish
Article number022607
JournalPhysical Review E
Volume103
Issue number2
DOIs
Publication statusPublished - Feb 2021

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