Simple chiral sulfonamide primary amine catalysed highly enantioselective Michael addition of malonates to enones

Chunhua Luo; Yu Jin; Da Ming Du

doi:10.1039/c2ob07191f

Simple chiral sulfonamide primary amine catalysed highly enantioselective Michael addition of malonates to enones

Chunhua Luo, Yu Jin, Da Ming Du^*

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

A chiral sulfonamide primary amine-organocatalysed, highly enantioselective Michael addition of malonates to enones has been developed. This reaction afforded the corresponding products in excellent yields (up to 99%) and excellent enantioselectivity (up to 99% ee).

Original language	English
Pages (from-to)	4116-4123
Number of pages	8
Journal	Organic and Biomolecular Chemistry
Volume	10
Issue number	20
DOIs	https://doi.org/10.1039/c2ob07191f
Publication status	Published - 28 May 2012

Access to Document

10.1039/c2ob07191f

Cite this

@article{c14bc86e70cc4bcc8f393b381b6ecdad,

title = "Simple chiral sulfonamide primary amine catalysed highly enantioselective Michael addition of malonates to enones",

abstract = "A chiral sulfonamide primary amine-organocatalysed, highly enantioselective Michael addition of malonates to enones has been developed. This reaction afforded the corresponding products in excellent yields (up to 99\%) and excellent enantioselectivity (up to 99\% ee).",

author = "Chunhua Luo and Yu Jin and Du, \{Da Ming\}",

year = "2012",

month = may,

day = "28",

doi = "10.1039/c2ob07191f",

language = "English",

volume = "10",

pages = "4116--4123",

journal = "Organic and Biomolecular Chemistry",

issn = "1477-0520",

publisher = "Royal Society of Chemistry",

number = "20",

}

TY - JOUR

T1 - Simple chiral sulfonamide primary amine catalysed highly enantioselective Michael addition of malonates to enones

AU - Luo, Chunhua

AU - Jin, Yu

AU - Du, Da Ming

PY - 2012/5/28

Y1 - 2012/5/28

N2 - A chiral sulfonamide primary amine-organocatalysed, highly enantioselective Michael addition of malonates to enones has been developed. This reaction afforded the corresponding products in excellent yields (up to 99%) and excellent enantioselectivity (up to 99% ee).

AB - A chiral sulfonamide primary amine-organocatalysed, highly enantioselective Michael addition of malonates to enones has been developed. This reaction afforded the corresponding products in excellent yields (up to 99%) and excellent enantioselectivity (up to 99% ee).

UR - https://www.scopus.com/pages/publications/84860742856

U2 - 10.1039/c2ob07191f

DO - 10.1039/c2ob07191f

M3 - Article

AN - SCOPUS:84860742856

SN - 1477-0520

VL - 10

SP - 4116

EP - 4123

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 20

ER -

Simple chiral sulfonamide primary amine catalysed highly enantioselective Michael addition of malonates to enones

Abstract

Access to Document

Other files and links

Fingerprint

Cite this