Separation of salsolinol using β-cyclodextrin-modified chiral membrane

Rong Ji Dai; Cai Lian Su; Hai Yan Wu; Yu Lin Deng

Separation of salsolinol using β-cyclodextrin-modified chiral membrane

Rong Ji Dai^*, Cai Lian Su, Hai Yan Wu, Yu Lin Deng

^*Corresponding author for this work

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

β-cyclodextrin-modified membrane was applied in the chiral separation of 1-methyl-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline (Salsolinol). From the results of HPLC, it was observed that β-cyclodextrin-modified membrane possess the ability of chiral discrimination to the Sal. Through one time diosmosis experiment of membrane circulation, the proportion of Sal changed from 0.87 to 1.55. Gaussian 98 software was used to study the difference of interaction energies between R, S-Sal with β-CD. Calculation were carried out in order to study the relevant mechanism.

Original language	English
Pages (from-to)	557-559+564
Journal	Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology
Volume	28
Issue number	6
Publication status	Published - Jun 2008

Keywords

Chiral separation
HPLC
Salsolinol
β-cyclodextrin

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title = "Separation of salsolinol using β-cyclodextrin-modified chiral membrane",

abstract = "β-cyclodextrin-modified membrane was applied in the chiral separation of 1-methyl-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline (Salsolinol). From the results of HPLC, it was observed that β-cyclodextrin-modified membrane possess the ability of chiral discrimination to the Sal. Through one time diosmosis experiment of membrane circulation, the proportion of Sal changed from 0.87 to 1.55. Gaussian 98 software was used to study the difference of interaction energies between R, S-Sal with β-CD. Calculation were carried out in order to study the relevant mechanism.",

keywords = "Chiral separation, HPLC, Salsolinol, β-cyclodextrin",

author = "Dai, {Rong Ji} and Su, {Cai Lian} and Wu, {Hai Yan} and Deng, {Yu Lin}",

year = "2008",

month = jun,

language = "English",

volume = "28",

pages = "557--559+564",

journal = "Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology",

issn = "1001-0645",

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TY - JOUR

T1 - Separation of salsolinol using β-cyclodextrin-modified chiral membrane

AU - Dai, Rong Ji

AU - Su, Cai Lian

AU - Wu, Hai Yan

AU - Deng, Yu Lin

PY - 2008/6

Y1 - 2008/6

N2 - β-cyclodextrin-modified membrane was applied in the chiral separation of 1-methyl-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline (Salsolinol). From the results of HPLC, it was observed that β-cyclodextrin-modified membrane possess the ability of chiral discrimination to the Sal. Through one time diosmosis experiment of membrane circulation, the proportion of Sal changed from 0.87 to 1.55. Gaussian 98 software was used to study the difference of interaction energies between R, S-Sal with β-CD. Calculation were carried out in order to study the relevant mechanism.

AB - β-cyclodextrin-modified membrane was applied in the chiral separation of 1-methyl-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline (Salsolinol). From the results of HPLC, it was observed that β-cyclodextrin-modified membrane possess the ability of chiral discrimination to the Sal. Through one time diosmosis experiment of membrane circulation, the proportion of Sal changed from 0.87 to 1.55. Gaussian 98 software was used to study the difference of interaction energies between R, S-Sal with β-CD. Calculation were carried out in order to study the relevant mechanism.

KW - Chiral separation

KW - HPLC

KW - Salsolinol

KW - β-cyclodextrin

UR - http://www.scopus.com/inward/record.url?scp=47049127665&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:47049127665

SN - 1001-0645

VL - 28

SP - 557-559+564

JO - Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology

JF - Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology

IS - 6

ER -

Separation of salsolinol using β-cyclodextrin-modified chiral membrane

Abstract

Keywords

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