Sceletorines A and B, two minor novel dimeric alkaloids of Mesembryanthemum tortuosum (synonym Sceletium tortuosum)

Hongquan Yin; Zulfiqar Ali; Yuanqing Ding; Yan Hong Wang; Michael J. Cunningham; Mohamed A. Ibrahim; Amar G. Chittiboyina; Wei Wang; Alvaro M. Viljoen; Ikhlas A. Khan

doi:10.1016/j.phytol.2019.03.013

Sceletorines A and B, two minor novel dimeric alkaloids of Mesembryanthemum tortuosum (synonym Sceletium tortuosum)

Hongquan Yin
, Zulfiqar Ali^*
, Yuanqing Ding
, Yan Hong Wang
, Michael J. Cunningham
, Mohamed A. Ibrahim
, Amar G. Chittiboyina
, Wei Wang
, Alvaro M. Viljoen
, Ikhlas A. Khan

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

University of Mississippi
Hunan University of Chinese Medicine
Tshwane University of Technology

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Sceletorines A and B, two unique alkaloids, were isolated for the first time from the aerial parts of Mesembryanthemum tortuosum. Their structures were determined by the extensive spectroscopic methods and their absolute configuration was established with ECD calculations. Plausible biosynthetic pathways for 1 and 2 are proposed and a relationship to the previously assumed artifact, channaine is also addressed.

Original language	English
Pages (from-to)	78-84
Number of pages	7
Journal	Phytochemistry Letters
Volume	31
DOIs	https://doi.org/10.1016/j.phytol.2019.03.013
Publication status	Published - Jun 2019

Keywords

Absolute configuration
Alkaloids
Mesembryanthemum tortuosum
NMR
Sceletium tortuosum
Sceletorine
Structure elucidation

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10.1016/j.phytol.2019.03.013

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title = "Sceletorines A and B, two minor novel dimeric alkaloids of Mesembryanthemum tortuosum (synonym Sceletium tortuosum)",

abstract = "Sceletorines A and B, two unique alkaloids, were isolated for the first time from the aerial parts of Mesembryanthemum tortuosum. Their structures were determined by the extensive spectroscopic methods and their absolute configuration was established with ECD calculations. Plausible biosynthetic pathways for 1 and 2 are proposed and a relationship to the previously assumed artifact, channaine is also addressed.",

keywords = "Absolute configuration, Alkaloids, Mesembryanthemum tortuosum, NMR, Sceletium tortuosum, Sceletorine, Structure elucidation",

author = "Hongquan Yin and Zulfiqar Ali and Yuanqing Ding and Wang, \{Yan Hong\} and Cunningham, \{Michael J.\} and Ibrahim, \{Mohamed A.\} and Chittiboyina, \{Amar G.\} and Wei Wang and Viljoen, \{Alvaro M.\} and Khan, \{Ikhlas A.\}",

note = "Publisher Copyright: {\textcopyright} 2019",

year = "2019",

month = jun,

doi = "10.1016/j.phytol.2019.03.013",

language = "English",

volume = "31",

pages = "78--84",

journal = "Phytochemistry Letters",

issn = "1874-3900",

publisher = "Elsevier Ltd.",

}

TY - JOUR

T1 - Sceletorines A and B, two minor novel dimeric alkaloids of Mesembryanthemum tortuosum (synonym Sceletium tortuosum)

AU - Yin, Hongquan

AU - Ali, Zulfiqar

AU - Ding, Yuanqing

AU - Wang, Yan Hong

AU - Cunningham, Michael J.

AU - Ibrahim, Mohamed A.

AU - Chittiboyina, Amar G.

AU - Wang, Wei

AU - Viljoen, Alvaro M.

AU - Khan, Ikhlas A.

PY - 2019/6

Y1 - 2019/6

N2 - Sceletorines A and B, two unique alkaloids, were isolated for the first time from the aerial parts of Mesembryanthemum tortuosum. Their structures were determined by the extensive spectroscopic methods and their absolute configuration was established with ECD calculations. Plausible biosynthetic pathways for 1 and 2 are proposed and a relationship to the previously assumed artifact, channaine is also addressed.

AB - Sceletorines A and B, two unique alkaloids, were isolated for the first time from the aerial parts of Mesembryanthemum tortuosum. Their structures were determined by the extensive spectroscopic methods and their absolute configuration was established with ECD calculations. Plausible biosynthetic pathways for 1 and 2 are proposed and a relationship to the previously assumed artifact, channaine is also addressed.

KW - Absolute configuration

KW - Alkaloids

KW - Mesembryanthemum tortuosum

KW - NMR

KW - Sceletium tortuosum

KW - Sceletorine

KW - Structure elucidation

UR - https://www.scopus.com/pages/publications/85063353805

U2 - 10.1016/j.phytol.2019.03.013

DO - 10.1016/j.phytol.2019.03.013

M3 - Article

AN - SCOPUS:85063353805

SN - 1874-3900

VL - 31

SP - 78

EP - 84

JO - Phytochemistry Letters

JF - Phytochemistry Letters

ER -

Sceletorines A and B, two minor novel dimeric alkaloids of Mesembryanthemum tortuosum (synonym Sceletium tortuosum)

Abstract

Keywords

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