Ruthenium-catalyzed C-h oxygenation on aryl Weinreb amides

Fanzhi Yang, Lutz Ackermann*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

110 Citations (Scopus)

Abstract

Versatile ruthenium catalysts enabled unprecedented C-H bond oxygenations of aryl Weinreb amides with ample scope under exceedingly mild reaction conditions, thereby also giving access to valuable ortho-hydroxylated aldehydes. Mechanistic studies provided strong support for a kinetically relevant C-H bond activation.

Original languageEnglish
Pages (from-to)718-720
Number of pages3
JournalOrganic Letters
Volume15
Issue number3
DOIs
Publication statusPublished - 1 Feb 2013
Externally publishedYes

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