Rhabdastrellins A-F, isomalabaricane triterpenes from the marine sponge Rhabdastrella aff. distincta

Fang Lv, Minjuan Xu, Zhiwei Deng, Nicole J. De Voogd, Rob W.M. Van Soest, Peter Proksch, Wenhan Lin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

Chemical examination of the marine sponge Rhabdastrella aff. distincta resulted in the isolation of six new isomalabaricane triterpenes, rhabdastrellins A-F (1-6), which were present as minor components, along with stellettins L and M. Their structures were elucidated on the basis of extensive spectroscopic data analyses and comparison with spectroscopic data of known analogues. The cytotoxicity of compounds 1-6 against a small panel of human tumor cell lines was also evaluated.

Original languageEnglish
Pages (from-to)1738-1741
Number of pages4
JournalJournal of Natural Products
Volume71
Issue number10
DOIs
Publication statusPublished - Oct 2008

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