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Research progress of pomalidomide in the treatment of relapsed refractory multiple myeloma

  • Songlin Chu
  • , Liansheng Zhang*
  • *Corresponding author for this work
  • Lanzhou University

Research output: Contribution to journalReview articlepeer-review

Abstract

Pomalidomide,which represents a new generation of immunomodulatory drugs (IMiD), has brought a major shift in therapeutic paradigm in treating relapsed and refractory multiple myeloma (RRMM). Considering its encouraging effectiveness, the U.S. Food and Drug Administration (FDA) approved its usage to treat patients who fail to respond to at least two prior therapies, including lenalidomide and bortezomib, and whose disease progressed within 60 days of the last treatment. This review summarizes the mechanisms of action and clinical activity of pomalidomide in treating RRMM.

Original languageEnglish
Pages (from-to)179-181
Number of pages3
JournalJournal of Leukemia and Lymphoma
Volume23
Issue number3
DOIs
Publication statusPublished - 2014
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Immunomodulatory drugs
  • Multiple myeloma
  • Pomalidomide

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