Recognition-Mediated Electrochemiluminescence Sensors: Recent Five-Year Breakthroughs and Future Directions in Acute Myocardial Infarction Biomarker Analysis

Shan Nan; Ziyu Zhu; Yao Xie; Fan Wang; Tianjian Lv; Yuan Gao; Pengyu Wang; Heao Zhang; Axin Liang

doi:10.1007/s41664-026-00456-4

Recognition-Mediated Electrochemiluminescence Sensors: Recent Five-Year Breakthroughs and Future Directions in Acute Myocardial Infarction Biomarker Analysis

Shan Nan
, Ziyu Zhu
, Yao Xie
, Fan Wang
, Tianjian Lv
, Yuan Gao
, Pengyu Wang
, Heao Zhang^*
, Axin Liang^*

^*Corresponding author for this work

School of Life Science

Beijing Institute of Technology
Ltd.
Hunan Academy of Social Sciences

Research output: Contribution to journal › Review article › peer-review

Abstract

Acute myocardial infarction (AMI) is the most severe type of cardiovascular and cerebrovascular diseases (CVDs). Therefore, it is critical to identify markers related to the occurrence, development, and prognosis of AMI. Electrochemiluminescence (ECL) involves forming excited state species through electron transfer, which results in the emission of light. ECL sensors do not require an additional light source and have been widely explored for the detection of AMI markers due to their high sensitivity and specificity. Here, based on the three types of recognition elements (immunity, aptamer, and specific nucleic acid) found in ECL sensors, we review their recent detection of AMI markers and analyze the challenges and prospects of their future application in this field.

Original language	English
Journal	Journal of Analysis and Testing
DOIs	https://doi.org/10.1007/s41664-026-00456-4
Publication status	Accepted/In press - 2026

Keywords

Acute myocardial infarction markers
Aptamer
Electrochemiluminescence
Immunosensor
Nucleic acid hybridization

Access to Document

10.1007/s41664-026-00456-4

Cite this

@article{0900860dc8a041e6bfe799a12e8f6777,

title = "Recognition-Mediated Electrochemiluminescence Sensors: Recent Five-Year Breakthroughs and Future Directions in Acute Myocardial Infarction Biomarker Analysis",

abstract = "Acute myocardial infarction (AMI) is the most severe type of cardiovascular and cerebrovascular diseases (CVDs). Therefore, it is critical to identify markers related to the occurrence, development, and prognosis of AMI. Electrochemiluminescence (ECL) involves forming excited state species through electron transfer, which results in the emission of light. ECL sensors do not require an additional light source and have been widely explored for the detection of AMI markers due to their high sensitivity and specificity. Here, based on the three types of recognition elements (immunity, aptamer, and specific nucleic acid) found in ECL sensors, we review their recent detection of AMI markers and analyze the challenges and prospects of their future application in this field.",

keywords = "Acute myocardial infarction markers, Aptamer, Electrochemiluminescence, Immunosensor, Nucleic acid hybridization",

author = "Shan Nan and Ziyu Zhu and Yao Xie and Fan Wang and Tianjian Lv and Yuan Gao and Pengyu Wang and Heao Zhang and Axin Liang",

note = "Publisher Copyright: {\textcopyright} The Nonferrous Metals Society of China 2026.",

year = "2026",

doi = "10.1007/s41664-026-00456-4",

language = "English",

journal = "Journal of Analysis and Testing",

issn = "2096-241X",

publisher = "Springer International Publishing",

}

TY - JOUR

T1 - Recognition-Mediated Electrochemiluminescence Sensors

T2 - Recent Five-Year Breakthroughs and Future Directions in Acute Myocardial Infarction Biomarker Analysis

AU - Nan, Shan

AU - Zhu, Ziyu

AU - Xie, Yao

AU - Wang, Fan

AU - Lv, Tianjian

AU - Gao, Yuan

AU - Wang, Pengyu

AU - Zhang, Heao

AU - Liang, Axin

PY - 2026

Y1 - 2026

N2 - Acute myocardial infarction (AMI) is the most severe type of cardiovascular and cerebrovascular diseases (CVDs). Therefore, it is critical to identify markers related to the occurrence, development, and prognosis of AMI. Electrochemiluminescence (ECL) involves forming excited state species through electron transfer, which results in the emission of light. ECL sensors do not require an additional light source and have been widely explored for the detection of AMI markers due to their high sensitivity and specificity. Here, based on the three types of recognition elements (immunity, aptamer, and specific nucleic acid) found in ECL sensors, we review their recent detection of AMI markers and analyze the challenges and prospects of their future application in this field.

AB - Acute myocardial infarction (AMI) is the most severe type of cardiovascular and cerebrovascular diseases (CVDs). Therefore, it is critical to identify markers related to the occurrence, development, and prognosis of AMI. Electrochemiluminescence (ECL) involves forming excited state species through electron transfer, which results in the emission of light. ECL sensors do not require an additional light source and have been widely explored for the detection of AMI markers due to their high sensitivity and specificity. Here, based on the three types of recognition elements (immunity, aptamer, and specific nucleic acid) found in ECL sensors, we review their recent detection of AMI markers and analyze the challenges and prospects of their future application in this field.

KW - Acute myocardial infarction markers

KW - Aptamer

KW - Electrochemiluminescence

KW - Immunosensor

KW - Nucleic acid hybridization

UR - https://www.scopus.com/pages/publications/105044345589

U2 - 10.1007/s41664-026-00456-4

DO - 10.1007/s41664-026-00456-4

M3 - Review article

AN - SCOPUS:105044345589

SN - 2096-241X

JO - Journal of Analysis and Testing

JF - Journal of Analysis and Testing

ER -

Recognition-Mediated Electrochemiluminescence Sensors: Recent Five-Year Breakthroughs and Future Directions in Acute Myocardial Infarction Biomarker Analysis

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this