Recent advances in hepatitis virus neutralizing antibody research

Mengyuan Zhao, Minghui Yang*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Hepatitis viruses constitute a significant global health threat, resulting in substantial morbidity and mortality on a global scale. The pursuit of effective therapeutic strategies to combat hepatitis virus infections remains a paramount objective within the realm of medical research. Among the promising candidates, neutralizing antibodies (NAbs) have emerged as noteworthy therapeutic agents due to their capacity to impede viral entry and replication. This chapter provides an overview of recent advancements in the investigation of NAbs targeting various hepatitis viruses, encompassing hepatitis A, B, C, D, and E viruses. Our discourse delves into elucidating the mechanisms underlying neutralization, as well as their practical applications in the therapeutic domain. Additionally, we shed light on the challenges inherent in this research area and delineate the prospective trajectories for future exploration.

Original languageEnglish
Title of host publicationNeutralizing Antibodies and their Role in Health and Disease
PublisherNova Science Publishers, Inc.
Pages111-134
Number of pages24
ISBN (Electronic)9798891137011
ISBN (Print)9798891135413
Publication statusPublished - 2 Apr 2024
Externally publishedYes

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