Pyrolysis-gas chromatography investigation of peralkylated β-cyclodextrins used as a capillary GC stationary phase

Six peralkylated β-cyclodextrins used as a GC stationary phase for the separation of positional and optical isomers were characterized by Py-GC. The Py-GC results showed that long-chain alkylated cyclodextrins are more thermally stable than those with short chains. Their degree of alkylation was also studied by thermally assisted hydrolysis and methylation in Py-GC. The capillary columns coated with these β-cyclodextrin derivatives showed excellent separation of some optical isomers.