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Preliminary investigation of second-order dispersion for noninvasively measuring glucose concentration in human body

  • Juan Liu*
  • , Shuisheng Jian
  • *Corresponding author for this work
  • Beijing Jiaotong University

Research output: Contribution to journalArticlepeer-review

Abstract

A possibility to measure glucose concentration using a Michelson partial coherent interferometer (LCD) is presented. For three different glucose concentrations, 0.18 mg/mL (hypoglycemia), 0.95 mg/mL (normal level) and 3.36 mg/mL (hyperglycemia) the second-order dispersion is investigated over the wavelength range 0.5 μm to 0.85 μm, and the investigation shows that different concentrations are associated with different second-order dispersions. The second-order dispersions for wavelengths from 0.55 μm to 0.8 μm are determined by Fourier analysis of the interferogram. This approach can be applied to measure the second-order dispersion for distinguishing the different glucose concentrations. It can be expected as a potentially noninvasive method to measure glucose concentration in human body.

Original languageEnglish
Pages (from-to)1297-1300
Number of pages4
JournalGuangxue Xuebao/Acta Optica Sinica
Volume24
Issue number10
Publication statusPublished - Oct 2004
Externally publishedYes

Keywords

  • Applied optics
  • Glucose concentration
  • Low coherence interferometer
  • Medical information processing
  • Second-order dispersion

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