Population parametrization of costly black box models using iterations between SAEM algorithm and kriging

  • Emmanuel Grenier
  • , Celine Helbert
  • , Violaine Louvet
  • , Adeline Samson
  • , Paul Vigneaux*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

In this article we focus on parametrization of black box models from repeated measurements among several individuals (population parametrization). We introduce a variant of the SAEM algorithm, called KSAEM algorithm, which couples the standard SAEM algorithm with the dynamic construction of an approximate metamodel. The costly evaluation of the genuine black box is replaced by a kriging step, using a basis of precomputed values, basis which is enlarged during SAEM algorithm to improve the accuracy of the metamodel in regions of interest.

Original languageEnglish
Pages (from-to)161-173
Number of pages13
JournalComputational and Applied Mathematics
Volume37
Issue number1
DOIs
Publication statusPublished - 1 Mar 2018
Externally publishedYes

Keywords

  • KPP equation
  • Kriging
  • Non-linear mixed effect models
  • Parameters estimation
  • Partial differential equations
  • SAEM algorithm

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