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Photoacoustic probe of targeting intracellular Staphylococcus aureus infection with signal-enhanced by self-assembly

  • Xin Jin
  • , Yue Fei
  • , Jingmei Ma
  • , Li Li Li
  • , Hao Wang*
  • *Corresponding author for this work
  • National Center for Nanoscience and Technology

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

In this chapter, we introduce the photoacoustic imaging probe in detecting the infection of bacterial in host cells. We give detailed protocols for the synthesis and confirmation of a PA probe which response to caspase-1 and then self-assembly to enhance the signal. With this PA contrast agent, we may provide a new approach for an intracellular bacterial infection with the selective and sensitive diagnosis.

Original languageEnglish
Title of host publicationPhotoacoustic Probes for In Vivo Imaging
EditorsJefferson Chan
PublisherAcademic Press Inc.
Pages331-347
Number of pages17
ISBN (Print)9780323855303
DOIs
Publication statusPublished - Jan 2021
Externally publishedYes

Publication series

NameMethods in Enzymology
Volume657
ISSN (Print)0076-6879
ISSN (Electronic)1557-7988

Keywords

  • Intracellular infection
  • Photoacoustic probe
  • Self-assembly

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