One-Pot Synthesis of 4(3/-/)-Quinazolinone under Base Condition

Change Liu; Qiyao Yu; Jianhonga Tang; Jiarong Li

doi:10.6023/cjoc1108102

One-Pot Synthesis of 4(3/-/)-Quinazolinone under Base Condition

Change Liu^*
, Qiyao Yu
, Jianhonga Tang
, Jiarong Li

^*Corresponding author for this work

School of Mechatronical Engineering

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

A series of 4(3H)-quinazolinones 3 were obtained from the one-pot synthesis of available substituted aromatic o-aminonitriles 1 with aldehydes 2 in the present of base. This tandem transformation was included in addition, intramolecular Pinner reaction, Dimroth rearrangement and oxidative dehydrogenation. The structures of products were characterized by 1 ^H NMR, 13 ^C NMR, IR spectra and elemental analysis.

Original language	English
Pages (from-to)	532-537
Number of pages	6
Journal	Chinese Journal of Organic Chemistry
Volume	32
Issue number	3
DOIs	https://doi.org/10.6023/cjoc1108102
Publication status	Published - Mar 2012

Keywords

4(3H)-quinazolinone
Aldehyde
Aromatic o-aminonitrile
Base catalysis
One-pot synthesis

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10.6023/cjoc1108102

Cite this

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abstract = "A series of 4(3H)-quinazolinones 3 were obtained from the one-pot synthesis of available substituted aromatic o-aminonitriles 1 with aldehydes 2 in the present of base. This tandem transformation was included in addition, intramolecular Pinner reaction, Dimroth rearrangement and oxidative dehydrogenation. The structures of products were characterized by 1 H NMR, 13 C NMR, IR spectra and elemental analysis.",

keywords = "4(3H)-quinazolinone, Aldehyde, Aromatic o-aminonitrile, Base catalysis, One-pot synthesis",

author = "Change Liu and Qiyao Yu and Jianhonga Tang and Jiarong Li",

year = "2012",

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pages = "532--537",

journal = "Chinese Journal of Organic Chemistry",

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T1 - One-Pot Synthesis of 4(3/-/)-Quinazolinone under Base Condition

AU - Liu, Change

AU - Yu, Qiyao

AU - Tang, Jianhonga

AU - Li, Jiarong

PY - 2012/3

Y1 - 2012/3

N2 - A series of 4(3H)-quinazolinones 3 were obtained from the one-pot synthesis of available substituted aromatic o-aminonitriles 1 with aldehydes 2 in the present of base. This tandem transformation was included in addition, intramolecular Pinner reaction, Dimroth rearrangement and oxidative dehydrogenation. The structures of products were characterized by 1 H NMR, 13 C NMR, IR spectra and elemental analysis.

AB - A series of 4(3H)-quinazolinones 3 were obtained from the one-pot synthesis of available substituted aromatic o-aminonitriles 1 with aldehydes 2 in the present of base. This tandem transformation was included in addition, intramolecular Pinner reaction, Dimroth rearrangement and oxidative dehydrogenation. The structures of products were characterized by 1 H NMR, 13 C NMR, IR spectra and elemental analysis.

KW - 4(3H)-quinazolinone

KW - Aldehyde

KW - Aromatic o-aminonitrile

KW - Base catalysis

KW - One-pot synthesis

UR - https://www.scopus.com/pages/publications/84861973619

U2 - 10.6023/cjoc1108102

DO - 10.6023/cjoc1108102

M3 - Article

AN - SCOPUS:84861973619

SN - 0253-2786

VL - 32

SP - 532

EP - 537

JO - Chinese Journal of Organic Chemistry

JF - Chinese Journal of Organic Chemistry

IS - 3

ER -

One-Pot Synthesis of 4(3/-/)-Quinazolinone under Base Condition

Abstract

Keywords

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