New drugs for the treatment of osteogenesis imperfecta: Research advances

Fang Lv; Mei Li

doi:10.13220/j.cnki.jipr.2017.02.016

New drugs for the treatment of osteogenesis imperfecta: Research advances

Fang Lv
, Mei Li^*

^*Corresponding author for this work

Chinese Academy of Medical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Osteogenesis imperfecta(OI)is a genetic bone disease characterized by increased bone fragility and recurrent bone fractures. It belongs to orphan diseases of which the diagnosis and treatment are facing challenges. The effective treatments targeting at the underlying causes are still unavailable. Recently, many agents have been demonstrated to increase bone mineral density, improve bone microstructures, and reduce the incidence of fractures. Herein, we review the progress in new drugs for the treatment of OI.

Original language	English
Pages (from-to)	173-177
Number of pages	5
Journal	Journal of International Pharmaceutical Research
Volume	44
Issue number	2
DOIs	https://doi.org/10.13220/j.cnki.jipr.2017.02.016
Publication status	Published - 28 Feb 2017
Externally published	Yes

Keywords

Orphan drug
Osteogenesis imperfect
Rare disease

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10.13220/j.cnki.jipr.2017.02.016

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AB - Osteogenesis imperfecta(OI)is a genetic bone disease characterized by increased bone fragility and recurrent bone fractures. It belongs to orphan diseases of which the diagnosis and treatment are facing challenges. The effective treatments targeting at the underlying causes are still unavailable. Recently, many agents have been demonstrated to increase bone mineral density, improve bone microstructures, and reduce the incidence of fractures. Herein, we review the progress in new drugs for the treatment of OI.

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New drugs for the treatment of osteogenesis imperfecta: Research advances

Abstract

Keywords

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