New Chiral Pyridine Prolinol Derivatives and Preliminary Study on Asymmetric Catalytic Reaction

Xiao Chen; Yong Xin Zhang; Da Ming Du; Wen Ting Hua

New Chiral Pyridine Prolinol Derivatives and Preliminary Study on Asymmetric Catalytic Reaction

Xiao Chen^*, Yong Xin Zhang, Da Ming Du, Wen Ting Hua

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Two new chiral pyridine prolinol derivatives have been synthesized from N-alkylation of (S)-α,α-diphenyl-2-pyrrolidinemethanol with 2-bromomethylpyridine and 2, 6-dibromomethyl-pyridine. The catalytic asymmetric borane reduction of prochiral ketones and the asymmetric addition of diethylzinc to benzaldehyde were investigated.

Original language	English
Pages (from-to)	167-168
Number of pages	2
Journal	Chinese Chemical Letters
Volume	15
Issue number	2
Publication status	Published - Feb 2004
Externally published	Yes

Keywords

Borane
Enantioselective reaction
Prolinol
Pyridine

Cite this

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title = "New Chiral Pyridine Prolinol Derivatives and Preliminary Study on Asymmetric Catalytic Reaction",

abstract = "Two new chiral pyridine prolinol derivatives have been synthesized from N-alkylation of (S)-α,α-diphenyl-2-pyrrolidinemethanol with 2-bromomethylpyridine and 2, 6-dibromomethyl-pyridine. The catalytic asymmetric borane reduction of prochiral ketones and the asymmetric addition of diethylzinc to benzaldehyde were investigated.",

keywords = "Borane, Enantioselective reaction, Prolinol, Pyridine",

author = "Xiao Chen and Zhang, \{Yong Xin\} and Du, \{Da Ming\} and Hua, \{Wen Ting\}",

year = "2004",

month = feb,

language = "English",

volume = "15",

pages = "167--168",

journal = "Chinese Chemical Letters",

issn = "1001-8417",

publisher = "Elsevier B.V.",

number = "2",

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TY - JOUR

T1 - New Chiral Pyridine Prolinol Derivatives and Preliminary Study on Asymmetric Catalytic Reaction

AU - Chen, Xiao

AU - Zhang, Yong Xin

AU - Du, Da Ming

AU - Hua, Wen Ting

PY - 2004/2

Y1 - 2004/2

N2 - Two new chiral pyridine prolinol derivatives have been synthesized from N-alkylation of (S)-α,α-diphenyl-2-pyrrolidinemethanol with 2-bromomethylpyridine and 2, 6-dibromomethyl-pyridine. The catalytic asymmetric borane reduction of prochiral ketones and the asymmetric addition of diethylzinc to benzaldehyde were investigated.

AB - Two new chiral pyridine prolinol derivatives have been synthesized from N-alkylation of (S)-α,α-diphenyl-2-pyrrolidinemethanol with 2-bromomethylpyridine and 2, 6-dibromomethyl-pyridine. The catalytic asymmetric borane reduction of prochiral ketones and the asymmetric addition of diethylzinc to benzaldehyde were investigated.

KW - Borane

KW - Enantioselective reaction

KW - Prolinol

KW - Pyridine

UR - https://www.scopus.com/pages/publications/1242296304

M3 - Article

AN - SCOPUS:1242296304

SN - 1001-8417

VL - 15

SP - 167

EP - 168

JO - Chinese Chemical Letters

JF - Chinese Chemical Letters

IS - 2

ER -

New Chiral Pyridine Prolinol Derivatives and Preliminary Study on Asymmetric Catalytic Reaction

Abstract

Keywords

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