Mining time-delayed coherent patterns in time series gene expression data

  • Linjun Yin*
  • , Guoren Wang
  • , Keming Mao
  • , Yuhai Zhao
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Citations (Scopus)

Abstract

Unlike previous pattern-based biclustering methods that focus on grouping objects on the same subset of dimensions, in this paper, we propose a novel model of coherent cluster for time series gene expression data, namely td-cluster (time-delayed cluster). Under this model, objects can be coherent on different subsets of dimensions if these objects follow a certain time-delayed relationship. Such a cluster can discover the cycle time of gene expression, which is essential in revealing the gene regulatory networks. This work is missed by previous research. A novel algorithm is also presented and implemented to mine all the significant td-clusters. Experimental results from both real and synthetic microarray datasets prove its effectiveness and efficiency.

Original languageEnglish
Title of host publicationAdvanced Data Mining and Applications - Second International Conference, ADMA 2006, Proceedings
EditorsXue Li, Osmar R. Zaïane, Zhanhuai Li
PublisherSpringer Verlag
Pages711-722
Number of pages12
ISBN (Print)3540370250, 9783540370253
DOIs
Publication statusPublished - 2006
Externally publishedYes
Event2nd International Conference on Advanced Data Mining and Applications, ADMA 2006 - Xi'an, China
Duration: 14 Aug 200616 Aug 2006

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume4093 LNAI
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference2nd International Conference on Advanced Data Mining and Applications, ADMA 2006
Country/TerritoryChina
CityXi'an
Period14/08/0616/08/06

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