Microwave-assisted synthesis of 2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones catalyzed by DBU in aqueous medium

Liupan Yang; Daxin Shi; Shu Chen; Hongxin Chai; Danfei Huang; Qi Zhang; Jiarong Li

doi:10.1039/c2gc16469h

Microwave-assisted synthesis of 2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones catalyzed by DBU in aqueous medium

Liupan Yang
, Daxin Shi
, Shu Chen
, Hongxin Chai
, Danfei Huang
, Qi Zhang
, Jiarong Li^*

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

46 Citations (Scopus)

Abstract

A clean green, efficient and facile protocol was developed for the synthesis of a series of 2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones in water with good yield by the reaction of 2-amino-nicotinonitriles with carbonyls catalyzed by DBU under microwave irradiation. The DBU–H₂O system can be recycled five times without activity loss.

Original language	English
Pages (from-to)	945-951
Number of pages	7
Journal	Green Chemistry
Volume	14
Issue number	4
DOIs	https://doi.org/10.1039/c2gc16469h
Publication status	Published - Apr 2012

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abstract = "A clean green, efficient and facile protocol was developed for the synthesis of a series of 2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones in water with good yield by the reaction of 2-amino-nicotinonitriles with carbonyls catalyzed by DBU under microwave irradiation. The DBU–H2O system can be recycled five times without activity loss.",

author = "Liupan Yang and Daxin Shi and Shu Chen and Hongxin Chai and Danfei Huang and Qi Zhang and Jiarong Li",

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AU - Yang, Liupan

AU - Shi, Daxin

AU - Chen, Shu

AU - Chai, Hongxin

AU - Huang, Danfei

AU - Zhang, Qi

AU - Li, Jiarong

PY - 2012/4

Y1 - 2012/4

N2 - A clean green, efficient and facile protocol was developed for the synthesis of a series of 2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones in water with good yield by the reaction of 2-amino-nicotinonitriles with carbonyls catalyzed by DBU under microwave irradiation. The DBU–H2O system can be recycled five times without activity loss.

AB - A clean green, efficient and facile protocol was developed for the synthesis of a series of 2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones in water with good yield by the reaction of 2-amino-nicotinonitriles with carbonyls catalyzed by DBU under microwave irradiation. The DBU–H2O system can be recycled five times without activity loss.

UR - https://www.scopus.com/pages/publications/84859124410

U2 - 10.1039/c2gc16469h

DO - 10.1039/c2gc16469h

M3 - Article

AN - SCOPUS:84859124410

SN - 1463-9262

VL - 14

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JF - Green Chemistry

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ER -

Microwave-assisted synthesis of 2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones catalyzed by DBU in aqueous medium

Abstract

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