Abstract
We developed a double-sided micro-well array microfluidic chip which consists of three parts: microfluidic channel, cell trapping array and cell lysate collecting chamber. We integrated single cell trapping, identification and in situ cell lysis in this microfluidic chip to differentiate Epidermal Growth Factor Receptor (EGFR)-expressed cancer cells from normal cells, for detecting not only the existence of EGFR expression, but also various mutation types at single cell level.
| Original language | English |
|---|---|
| Title of host publication | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 206-207 |
| Number of pages | 2 |
| ISBN (Electronic) | 9780979806490 |
| Publication status | Published - 2016 |
| Externally published | Yes |
| Event | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland Duration: 9 Oct 2016 → 13 Oct 2016 |
Publication series
| Name | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
|---|
Conference
| Conference | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
|---|---|
| Country/Territory | Ireland |
| City | Dublin |
| Period | 9/10/16 → 13/10/16 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Epidermal growth factor receptor mutation
- Genetic analysis
- Single cell analysis
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