Label-free identification carbapenem-resistant Escherichia coli based on surface-enhanced resonance Raman scattering†

Shengqi Wang, Bing Gu, Jia Li, Chongwen Wang, Haiquan Kang, Liting Shao, Lulu Hu, Rui Xiao

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)

Abstract

In this study, a surface-enhanced resonance Raman scattering (SERRS) method has been developed for the accurate detection and identification of carbapenem-resistant and carbapenem-sensitive Escherichia coli. A total of 89 human isolates of Enterobacteriaceae, comprising 41 strains of carbapenem-sensitive E. coli (CSEC) and 48 strains of carbapenem-resistant E. coli (CREC), were tested to assess the feasibility of our proposed SERRS method as a clinical tool, and the results showed almost 100% accuracy.

Original languageEnglish
Pages (from-to)4761-4765
Number of pages5
JournalRSC Advances
Volume8
Issue number9
DOIs
Publication statusPublished - 2018
Externally publishedYes

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