Isomalabaricane-type compounds from the marine sponge Rhabdastrella aff. distincta

Fang Lv; Zhiwei Deng; Jun Li; Hongzheng Fu; Rob W.M. Van Soest; Peter Proksch; Wenhan Lin

doi:10.1021/np040145+

Isomalabaricane-type compounds from the marine sponge Rhabdastrella aff. distincta

Fang Lv, Zhiwei Deng, Jun Li, Hongzheng Fu, Rob W.M. Van Soest, Peter Proksch, Wenhan Lin^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

44 Citations (Scopus)

Abstract

Fractionation of the marine sponge Rhabdastrella aff. distincta led to the isolation and characterization of four new isomalabaricane analogues, isogeoditin A (1), 13-(E)-isogeoditin A (2), isogeoditin B (3), and 22,23-dihydrostellettin B (4), along with seven known isomalabaricane derivatives (5-11). Methylation of 10 and 11 afforded methyl esters 12 and 13. The structures of compounds 1-4 were determined on the basis of spectroscopic data analysis. All compounds were tested against a small panel of human tumor cell lines.

Original language	English
Pages (from-to)	2033-2036
Number of pages	4
Journal	Journal of Natural Products
Volume	67
Issue number	12
DOIs	https://doi.org/10.1021/np040145+
Publication status	Published - Dec 2004
Externally published	Yes

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title = "Isomalabaricane-type compounds from the marine sponge Rhabdastrella aff. distincta",

abstract = "Fractionation of the marine sponge Rhabdastrella aff. distincta led to the isolation and characterization of four new isomalabaricane analogues, isogeoditin A (1), 13-(E)-isogeoditin A (2), isogeoditin B (3), and 22,23-dihydrostellettin B (4), along with seven known isomalabaricane derivatives (5-11). Methylation of 10 and 11 afforded methyl esters 12 and 13. The structures of compounds 1-4 were determined on the basis of spectroscopic data analysis. All compounds were tested against a small panel of human tumor cell lines.",

author = "Fang Lv and Zhiwei Deng and Jun Li and Hongzheng Fu and \{Van Soest\}, \{Rob W.M.\} and Peter Proksch and Wenhan Lin",

year = "2004",

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doi = "10.1021/np040145+",

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T1 - Isomalabaricane-type compounds from the marine sponge Rhabdastrella aff. distincta

AU - Lv, Fang

AU - Deng, Zhiwei

AU - Li, Jun

AU - Fu, Hongzheng

AU - Van Soest, Rob W.M.

AU - Proksch, Peter

AU - Lin, Wenhan

PY - 2004/12

Y1 - 2004/12

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AB - Fractionation of the marine sponge Rhabdastrella aff. distincta led to the isolation and characterization of four new isomalabaricane analogues, isogeoditin A (1), 13-(E)-isogeoditin A (2), isogeoditin B (3), and 22,23-dihydrostellettin B (4), along with seven known isomalabaricane derivatives (5-11). Methylation of 10 and 11 afforded methyl esters 12 and 13. The structures of compounds 1-4 were determined on the basis of spectroscopic data analysis. All compounds were tested against a small panel of human tumor cell lines.

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SN - 0163-3864

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SP - 2033

EP - 2036

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 12

ER -

Isomalabaricane-type compounds from the marine sponge Rhabdastrella aff. distincta

Abstract

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