Abstract
Binaphthyl sulfonimides have been developed to catalyze the asymmetric Michael addition of ketone to alkylidene malonates, affording the corresponding Michael products in good to high yields (up to 98%) with good to excellent diastereoselectivity (up to 99:1 dr) and enantioselectivity (up to 92% ee) under mild conditions using environmentally benign water as the solvent.
| Original language | English |
|---|---|
| Pages (from-to) | 2676-2680 |
| Number of pages | 5 |
| Journal | Chinese Journal of Chemistry |
| Volume | 30 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 2012 |
Keywords
- Michael addition
- asymmetric catalysis
- malonates
- organocatalysis
- sulfonimides